Front Cover; Immune Recognition and Evasion: Molecular Aspects of Host-Parasite Interaction; Copyright Page; Table of Contents; Preface; PART I: MECHANISMS AND GENETIC CONTROL OF IMMUNE RECOGNITION; Chapter 1. Genomic Organization of the T Cell Receptor; Introduction; Genomic Organization of the T Cell Receptor Genes; Conclusion; References; Chapter 2. Contribution of Non-B DNA Structures to Switch Recombination in Immunoglobulin Genes; Introduction; Results; Discussion; Acknowledgments; References.

Chapter 3. Biological Consequences of Signal Transduction by Class II Molecules Encoded by the Major Histocompatibility Complex laIntroduction; Results and Discussion; Conclusions; References; Chapter 4. Allelic Polymorphism of HLA Class II Antigens: Clues to the Molecular Basis of Autoimmunity; Introduction; MHC Class II Structure and Function; HLA and Disease; Conclusions; References; Chapter 5. Mimicry between HLA-B27 and Bacteria: A Spurious Finding or the Link Connecting HLA-B27 and Arthritogenic Bacteria?; Introduction; Cross-Reactivity Using Monoclonal Anti-B27 Antibodies.

Evidence for Mimicry Using Synthetic PeptidesGeneral Conclusion; Acknowledgments; References; Chapter 6. Genetic Control of Predisposition to Helminth Infection; Introduction; Generation of Predisposition; Analysis of Genetically Determined Predisposition; Conclusions; References; PART II: STRUCTURE OF ANTIGENIC EPITOPES: PARASITE ANTIGENS; Chapter 7. Recognition of Protein Antigens by Antibodies: Crystal Structure of Antibody Fab Fragments Complexed with Influenza Virus Neuraminidase; Introduction; Structure of Fab-NA Complexes; Escape Mutants; Structure of Escape Mutants.

Mechanisms of Inhibition of NA Activity by AntibodyAntibody Distortion; Acknowledgments; References; Chapter 8. Recognition of Influenza Antigens by Class I Restricted Cytotoxic T Lymphocytes; Introduction; Slightly Altered Versions of Self; How Are Cytoplasmic Antigens Recognized at the Cell Surface?; Recent Work; References; Chapter 9. The Origin of the Autoimmune Pathology Associated with Trypanosoma cruzi Infection; Introduction; Conclusions; References; Chapter 10. Advances toward a Vaccine against Schistosomiasis; Introduction; Protective Immunity against Schistosomes.

Target Antigens of ImmunityConclusions; References; Chapter 11. Stress Proteins as Immune Targets in Bacterial and Parasitic Infections; Introduction; Results and Discussion; Acknowledgments; References; PART III: CYTOKINES AND HORMONES IN HOST-PARASITE INTERACTION; Chapter 12. Autocrine-Stimulated Immortalization of Lymphocytes by the Parasite Theileria parva; Introduction; Life Cycle; Lymphocyte Proliferation in Vitro; Growth of Theileria in Nonbovine Cells and Animals; Host-Parasite Relationship; Acknowledgments; References.