Front Cover; Na+ -H+ Exchange, Intracellular pH, and Cell Function; Copyright Page; Contents; Preface; Yale Membrane Transport Processes Volumes; PART I: GENERAL ASPECTS OF INTRACELLULAR pH REGULATION AND Na+-H+ EXCHANGE; Chapter I. lntracellular pH Regulation by Leech and Other Invertebrate Neurons; I. Introduction; II. Methods; III. Results with Leech Neurons; IV. Conclusion; References; Chapter 2. Approaches for Studying lntracellular pH Regulation in Mammalian Renal Cells; I. Introduction; II. An Optical Absorbance Technique for Measuring lntracellular pH

III. lntracellular pH Regulation in Mammalian Renal CellsIV. Conclusions; References; Chapter 3. Aspects of pHi Regulation in Frog Skeletal Muscle; I. Introduction; II. Methods; Ill. Steady-State pH; IV. Response of pH1 to Acid Loading; V. Nature of pH1-Regulating Systems; VI. Properties of Na-H Exchange; VII. Factors Affecting the Rate of Na-H Exchange; VIII. Comparison with Other Cells; IX. Summary; References; Chapter 4. Molecular Properties and Physiological Roles of the Renal Na+-H + Exchanger; I. Introduction; II. Kinetics of the Renal Nat-H+ Exchanger

Ill. Biochemistry of the Renal Na+-H+ ExchangerIV. Role of the Renal Na+-Ht Exchanger in Facilitating Anion Transport; References; PART II. Na+-H+ EXCHANGE AND CELL VOLUME REGULATION; Chapter 5. Volume-Sensitive Alkali Metal-H Transport in Amphiuma Red Blood Cells; I. Introduction; II. Volume-Sensitive Fluxes in Amphiuma Red Blood Cells; Ill. The Effects of DlDS upon Alkali Metal-H Exchange by Osmotically Swollen Cells: Activation versus Altered Selectivity; IV. Activation of Alkali Metal-H Exchange: A Role for Diacylglycerol through Protein Kinase C

V. The Relationship between Na-H and K-H Exchange in Amphiuma Red Blood CellsVI. Summary; References; Chapter 6. Na-Proton Exchange in Dog Red Blood Cells; I. Introduction; II. Anion Requirement; III. Fixation of the Transport Mechanism by Glutaraldehyde; IV. Protein Fluxes; V. Lithium Effects; References; Chapter 7. Activation of the Na+-H+ Antiport by Changes in Cell Volume and by Phorbol Esters; Possible Role of Protein Kinase; I. Introduction; II. Basic Properties of Na+-Ht Exchange in Lymphocytes; III. Na+-H+ Exchange in Volume Regulation

IV. Stimulation of Na+-H+ Exchange by Phorbol EstersV. Similarities of the Phorbol Ester and Volume-Induced Activation; VI. Possible Involvement of a Protein Kinase in Volume Regulation; VII. Osmotically Induced Changes in Phosphoinositide Turnover; VIII. Concluding Remarks; References; PART III: Na+-H+ EXCHANGE AND CONTROL OF CELL GROWTH; Chapter 8. The Generation of Ionic Signals by Growth Factors; I. Introduction; II. Ionic Signals in Growth Factor Action; III. Possible Physiological Role of Inlracellular Ionic Changes