Front Cover; Advances in Pharmacology and Chemotherapy, Volume 8; Copyright Page; Contents; Contributors to This Volume; Chapter 1. Neurohumoral Mechanisms in the Brain Slice; I. Introduction; II. Uptake and Storage; III. Metabolism; IV. Release; V. Conclusions; References; Chapter 2. An Introduction to Immunosuppressants; I. Introduction; II. Immunosuppressants; III. Variables Which Determine the Success of an Immunosuppressive Regimen; IV. Immunosuppressive Mechanisms; V. Human Applications; References; Chapter 3. Glutamine Antagonists in Chemotherapy; I. Introduction

II. Biological Functions and Synthesis of L-GlutamineIII. Diazo Analogs of L-Glutamine; IV. Inhibitors of L-Glutamine Synthetase; V. L-Glutaminase; VI. Competitive Inhibitors of L-Glutaminyl t-RNA Synthesis; VII. Other Analogs; VIII. Possible Future Therapeutic Use of Analogs of L-Glutamine; IX. Glutamine Analogs and Other Compounds as Inhibitors of L-Asparagine Synthetase; References; Chapter 4. The Combined Action of Pyrimidines and Sulfonamides or Sulfones in the Chemotherapy of Malaria and Other Protozoal Infections; I. Introduction; II. Historical; III. Mode of Action

IV. The Long-Acting SulfonamidesV. Toxoplasmosis; VI. Coccidiosis; VII. Conclusions; References; Chapter 5. Chemotherapeutic Compounds Affecting DNA Structure and Function; I. Introduction; II. Combination with DNA by Intercalation; III. Interaction of Actinoniycin with DNA; IV. Chromomycins and Ari thracyclines; V. Cross-Linking by Mitomycins; VI. Diamidines, Polyamines, and Related Compounds; VII. Speculations on the Basis of Selective Toxicity; References; Note Added in Proof; Chapter 6. Interactions of Monoamine Oxidase Inhibitors, Amines, and Foodstuffs; I. Introduction

II. Amines in FoodstuffsIII. Metabolism of Amines and Related Substances in Foodstuffs; IV. Distribution of Monoamine Oxidase in the Body; V. Classification and Chemical Structure of Some Monoamine Oxidase Inhibitors; VI. Absorption of Amines and Amino Acids from the Intestine; VII. Effects of Amines Absorbed from Foodstuffs in the Intestine and Reaching the Systemic Circulation; VIII. Failure to Obtain Sympathomimetic Effects with Foods Containing Significant Amounts of Tyramine; IX. Interaction between and Autopotentiation of Monoamine Oxidase Inhibitors

X. Other Interactions with Monoamine Oxidase InhibitorsXI. Conclusion; References; Author Index; Subject Index