Programmed cell death. Part A, General principles for studying cell death
by
 
Khosravi-Far, Roya, editor.

Title
Programmed cell death. Part A, General principles for studying cell death

Author
Khosravi-Far, Roya, editor.

ISBN
9780080921648
 
9780123743121

Publication Information
San Diego, California : Academic Press/Elsevier, ©2008.

Physical Description
1 online resource (xlviii, 493 pages, 15 unnumbered pages of plates) : illustrations (some color).

Series
Methods in enzymology, v. 442
 
Methods in enzymology ; v. 442.

Contents
Analyzing morphological and ultrastructural features in cell death / A. Tinari [and others] -- Evaluation of some cell death features by real time real space microscopy / S. S. Smaili, T. R. Rosenstock and Y. T. Hsu -- Analysis of apoptotic pathways by multiparametric flow cytometry : application to HIV infection / H. Lecoeur [and others] -- Methods to analyze the palmitoylated CD95 high molecular weight death-inducing signaling complex / C. Feig and M. E. Peter -- Immunomagnetic isolation of tumor necrosis factor receptosomes / V. Tchikov and S. Schutze -- Analyzing lipid raft dynamics during cell apoptosis / W. Malorni [and others] -- Apoptosome assembly / Y. Shi -- Caspases : determination of their activities in apoptotic cells / A. Vaculova and B. Zhivotovsky -- Lysosomes in apoptosis / S. Ivanova [and others] -- More than two sides of a coin? : how to detect the multiple activities of type 2 transglutaminase / C. Rodolfo [and others] -- Granzymes and cell death / D. Martinvalet, J. Thiery and D. Chowdhury -- Investigation of the proapoptotic BCL-2 family member bid on the crossroad of the DNA damage response and apoptosis / S. S. Zinkel -- Assembly, purification, and assay of the activity of the ASC pyroptosome / T. Fernandes-Alnemri and E. S. Alnemri -- Nucleases in programmed cell death / K. Kawane and S. Nagata -- Detection of autophagy in cell death / Z. Zakeri, A. Melendez and R. A. Lockshin -- Methods for distinguishing apoptotic from necrotic cells and measuring their clearance / D. V. Krysko [and others] -- Two-dimensional gel-based analysis of the demolition phase of apoptosis / A. U. Luthi, S. P. Cullen and S. J. Martin -- Methods to dissect mitochondrial membrane permeabilization in the course of apoptosis / L. Galluzzi [and others] -- Oxidative lipidomics of programmed cell death / V. A. Tyurin [and others] -- Identification and characterization of endoplasmic reticulum stress-induced apoptosis in vivo / K. Zhang and R. J. Kaufman -- Organelle intermixing and membrane scrambling in cell death / M. Degli Esposti -- Mechanisms and methods in glucose metabolism and cell death / Y. Zhao [and others].

Abstract
The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. * This volume provides the necessary, trusted methods to carry out this research on the latest techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies. * Presents key methods on studying tumors and how these cancer cells evade cell death. * Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over.

Subject Term
Apoptosis.
 
Cancer cells -- Variation.
 
Apoptosis. (DNLM)D017209
 
SCIENCE -- Life Sciences -- Anatomy & Physiology.
 
Apoptosis. (OCoLC)fst00811467
 
Cancer cells -- Variation. (OCoLC)fst00845576

Genre
Electronic books.

Added Author
Khosravi-Far, Roya,
 
Zakeri, Zahra, 1952-
 
Lockshin, R. A. (Richard A.),
 
Piacentini, Mauro,

Electronic Access
ScienceDirect http://www.sciencedirect.com/science/book/9780123743121
 
ScienceDirect http://www.sciencedirect.com/science/bookseries/00766879/442
 
ScienceDirect http://www.sciencedirect.com/science/bookseries/00766879
 
ScienceDirect https://www.sciencedirect.com/science/bookseries/00766879/442


Shelf NumberItem BarcodeShelf LocationShelf LocationHolding Information
QP601 .M49 EB VOL. 4421190506-1001Elsevier E-Book CollectionsElsevier E-Book Collections