Front Cover; Production of Biologicals from Animal Cells in Culture; Copyright Page; Table of Contents; Hyclone Award Lecture; Chapter 1. Animal cell culture: the problems and rewards; Section 1: Cell lines and their characterization; Chapter 2. The isolation of immortal murine macrophage cell lines; ABSTRACT; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; ACKNOWLEDGEMENTS; REFERENCES; Chapter 3. Propagation of human CD4-immunoglobulin producing cell lines; Abstract; Introduction; Materials and Methods; Results and Discussions; References; Paper of Schlaeger

Chapter 4. Characterisation of cell banks by DNA fingerprintingINTRODUCTION; MATERIALS AND METHODS; RESULTS; CONCLUSIONS; REFERENCES; Paper of Stacey ; Chapter 5. Evaluating the safety of murine and human hybridomas: new problems and new techniques; David Onions1 and Gillian Lees2; ABSTRACT AND INTRODUCTION; SCREENING FOR MURINE RETROVIRUSES; HUMAN RETROVIRUSES; HERPESVIRUS SCREENING; PCR BASED TECHNIQUES; SUMMARY; REFERENCES; Chapter 6. Defective endogenous retroviruslike particles of Chinese hamster ovary cells; ABSTRACT; INTRODUCTION; MATERIALS AND METHODS; RESULTS; DISCUSSION

ACKNOWLEDGEMENTSREFERENCES; Paper of Anderson; Chapter 7. Reference cell lines; BACKGROUND; PROPOSAL; ACTION; REFERENCES; Chapter 8. A European database for animal cell lines; A Doyle*, J B Griffiths+ and C Caulcott; ABSTRACT; Chapter 9. Cell line data base: an on-line data bank where industry meets researchers; ABSTRACT; INTRODUCTION; TECHNICAL DESCRIPTION; CELL LINE DATA BASE; ACKNOWLEDGEMENTS; REFERENCES; Chapter 10. Adhesion and motility of embryonic and cancer cells; Paper of Thiery; Chapter 11. Immortalization of cells with oncogenes; Paper of Samarut

Section 2: Nutrient media with special supplementsChapter 12. Lipid metabolism of animal cells in culture -- a review; ABSTRACT; BACKGROUND; UTILIZATION OF EXTRACELLULAR LIPIDS; TURNOVER AND MODIFICATIONS OF CELL LIPID COMPOSITION; INFLUENCE OF LIPIDIC SUPPLEMENTS ON CELL GROWTH RATES; POTENTIAL IMPACT ON LARGE-SCALE MAMMALIAN CELL CULTURE; REFERENCES; Paper of Schmidt; Chapter 13. Lipoprotein requirements of cultured mammalian cells; ABSTRACT; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; CONCLUSION; REFERENCE

Chapter 14. Effect of nutrients and waste metabolites on growth, metabolism and protein synthesis in hybridomaABSTRACT; KEYWORDS ; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; REFERENCES; Chapter 15. Hybridoma growth, metabolism, and product formation in hepes-buffered medium: effect of passage number and pH; ABSTRACT; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; ACKNOWLEDGEMENTS; REFERENCES; Chapter 16. A screening experiment of media supplements on CHO cells; INTRODUCTION; EXPERIMENTAL DESIGN; MATERIALS AND METHODS; RESULTS AND DISCUSSION; CONCLUSION