Front Cover; Advances in Genetics: Molecular Genetics of Development; Copyright Page; Contents; Preface; Ernst W. Caspari: Geneticist, Teacher, and Mentor; Chapter 1. Heat-Shock Proteins and Development; I. Introduction and Overview; II. Heat-Shock Proteins and Development in Animal Systems; III. Heat-Shock Proteins and Development in Microorganisms; IV. Tissue-Culture Systems; V. Conclusion; References; Chapter 2. Mechanisms of Heat-Shock Gene Activation in Higher Eukaryotes; I. Introduction; II. The Heat-Shock Regulatory Element (HSE); III. The Heat-Shock Transcription Factor (HSTF)

IV. Heat Induction of Heat-Shock GenesV. Developmental Activation of Heat-Shock Genes; VI. Functions of Heat-Shock Proteins; VII. The Connection between Gene Activation and Function: A Hypothesis; Note Added in Proof; References; Chapter 3. Regulatory Gene Action during Eukaryotic Development; I. Introduction; II. Regulatory Genes of the Mouse; III. Regulatory Genes of Drosophila; IV. Regulatory Genes of Maize; V. Regulatory Genes of Rainbow Trout; VI. Discussion; References; Chapter 4. The Genetics of Biogenic Amine Metabolism, Sclerotization, and Melanization in Drosophila melanogaster

I. IntroductionII. General Comments on Biogenic Amine Metabolism; III. Biogenic Amine Metabolism in Drosophila; IV. Melanization, Quinone Sclerotization, and B-Sclerotization in Insects; V. Developmental Profiles of Catecholamine Pools during Embryogenesis and after Adult Eclosion in Drosophila; VI. The Genetics and Biology of Alkaline Phosphatase-1 and the Metabolism of Tyrosine-0-Phosphate; VII. Dopa Decarboxylase in D. melanogaster; VIII. Tyrosine and 5-Hydroxytryptophan Decarboxylase Activities; IX. The Genetics of a-Methyldopa Sensitivity and Resistance

X. The Ddc Cluster of Functionally Related GenesXI. The Genetics and Biology of Phenol Oxidase Activities; XII. Dopamine Acetyltransferase; XIII. The Genetics of ß-Alanine, Dopamine, and N-ß-Alanyldopamine Metabolism in Drosophila; XIV. Two Additional Body Color Mutations; XV. Concluding Remarks; References; Chapter 5. Developmental Control and Evolution in the Chorion Gene Families of Insects; I. Introduction; II. Sequences of Chorion Genes and Proteins; III. Chromosomal Organization and Developmental Expression of Chorion Genes; IV. The 5'-Flanking DNA Sequences of Chorion Genes

V. Evolutionary Conservation of Regulatory Elements among Flies and MothsReferences; Chapter 6. The Significance of Split Genes to Developmental Genetics; I. Introduction; II. The Concept of Maturase; III. Ontogeny; IV. Phylogeny; V. General Conclusion; References; Chapter 7. Gene Transfer into Mice; I. Preface; II. Introduction; III. Integration; IV. Translocations; V. Insertional Mutagenesis; VI. Gene Expression; VII. Developmental Stage-Specific Gene Expression; VIII. Oncology; IX. Immunology; X. Correction of Genetic Deficiencies; XI. Transgenic Mice as Models of Human Disease