Front Cover -- Advances in Clinical Chemistry, Volume 29 -- Copyright Page -- Contents -- Contributors -- Preface -- Chapter 1. Clinical Significances of Superoxide Dismutases: Changes in Aging, Diabetes, Ischemia, and Cancer -- 1. Introduction -- 2. Cu, Zn-SOD -- 3. Mn-SOD -- 4. Conclusion -- References -- Chapter 2. Biochemistry of the Uremic Syndrome -- 1. Introduction -- 2. Retention of Inorganic Substances -- 3. Retention of Organic Substances -- 4. The Loss of Hormones and Enzymes Produced by the Kidneys.

3. PCR in the Clinical Laboratory: Practical Applications -- 4. Specific Applications -- 5. Conclusion -- References -- Chapter 5. Oncogenes in Cancer -- 1. Carcinogenesis -- 2. Retroviruses and Oncogenes -- 3. Oncogene Characterization and Mode of Action -- 4. Basic Techniques Used in the Study of Oncogenes -- 5. Oncogenes and Cancer -- 6. Discussion -- 7. Prospects -- References -- Chapter 6. Gastrin and Cancer -- 1. Introduction -- 2. Definition of the Gastrin System -- 3. Homology of Human Gastrin with Other Peptides.

4. Expression and Synthesis of Antral Gastrin -- 5. Expression and Synthesis of Extraantral Gastrin -- 6. Modes of Secretion of Gastrin -- 7. Expression of Gastrin in Tumors -- 8. Gastrin as Tumor Growth Factor -- 9. Requirement for Gastrin Measurements in Clinical Oncology -- 10. Methods for Measurement of Gastrin -- References -- Chapter 7. A Biochemical Approach to Renal Stone Formation -- 1. Introduction -- 2. Matrix Theory -- 3. Conclusion -- References -- Index.

5. The Effects of the Uremic Environment -- 6. Dialysis-Related Problems -- 7. Drugs and Exogenous Toxins -- 8. Conclusions -- References -- Chapter 3. Renal Biochemistry and Physiology: Pathophysiology and Analytical Perspectives -- 1. Anatomical Features of the Kidney -- 2. Renal Physiology -- 3. Pathophysiology -- 4. Summation of Current Concepts -- 5. Perspectives for the Future -- References -- Chapter 4. The Polymerase Chain Reaction: Clinical Applications -- 1. Introduction -- 2. Principle of PCR.