Front Cover; Progress in Nucleic Acid Research and Molecular Biology, Volume 11; Copyright Page; Contents; List of Contributors; Preface; Abbreviations and Symbols; Some Articles Planned for Future Volumes; Chapter 1. The Induction of Interferon by Natural and Synthetic Polynucleotides; I. Introduction; II. The Induction of Interferon by Viruses; III. The Induction of Interferon by Nonviral Agents; IV. Double-Stranded RNA in Cells Infected with DNA-Containing Viruses; V. Discussion of the Mechanism of Induction of Interferon; References; Chapter 2. Ribonucleic Acid Maturation in Animal Cells.

I. The Concept of Molecular MaturationII. Ribosomal RNA Maturation; III. Maturation of tRSA; IV. Other RNA Species That might Arise Through Maturation Processes; V. Concluding Remarks; References; Chapter 3. Liporibonucleoprotein as an Integral Part of Animal Cell Membranes; I. Introduction; II. RNA Associated with Membranes; III. RNA-Lipoprotein Complexes; References; Chapter 4. Uptake of Nonviral Nucleic Acids by Mammalian Cells; I. Introduction; II. Uptake of Labeled DNA; III. Mechanisms of Uptake of DNA; IV. Biochemical Effects of DNA; V. Biological Effects of DNA.

VI. Uptake of Labeled RNAVII. Mechanism of Uptake of RNA; VIII. Biochemical Effects of RNA; IX. Biological Effects of RNA; X. Conclusions and Outlook; References; Chapter 5. The Relaxed Control Phenomenon; I. Introduction; II. Genetics; III. Anomalous Behavior of RCrel Mutank; IV. Parallelism between the Genetic Relaxed Response and Phenotypic Relaxation; V. Physiological Response of RCrel Mutants to Growth-Rate Transition; VI. Proposed Mechanisms for the Control of RNA Synthesis; VII. The Problem of Coordinate versus Noncoordinate Regulation; VIII. Epilogue; Note Added in Proof; References.

Chapter 6. Molecular Aspects of Genetic RecombinationI. Introduction; II. Paradigms of Recombination; III. The Recombination Cycle; IV. Recombination Systems in Procaryotes; V. DNA as a Target for the Recombination Event; VI. Conclusion; References; Chapter 7. Principles and Practices of Nucleic Acid Hybridization; I. Introduction; II. Yield of Hybrid as a Function of Reactant Concentration; III. Kinetics of the Hybridization Reaction; IV. Estimating Relative Transcribing Activities of DNA Sites; V. Quantitative Limitations of Hybridization; VI. Use of Competitor RYA to Estimate Specificity.

VII. Hybridization of Nucleic Acids from Eucaryotic CellsVIII. Conclusions; References; Chapter 8. Recent Studies Concerning the Coding Mechanism; I. Introduction-Present Status of the Code; II. Role of Ribosomes; III. Translation of Polycistronic Messenger RNA; IV. Redundancy; V. Intercistronic Sequences; VI. Universality; VII. Definition of the "Recognition Site" in tRNA Specifying Enzymatic Charging with the Correct Amino Acid; VIII. Molecular Evolution of tRNA Molecules; References; Chapter 9. The Ribosomal RNA Cistrons; I. Introduction; II. Multiplicity of the Ribosomal Cistrons.