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Advances in clinical chemistry
Title:
Advances in clinical chemistry
Author:
Makowski, Gregory S.
ISBN:
9780120103393
9781281004635
9781280633089
9786610633081
9780080458298
Publication Information:
New York : Academic Press, 2005.
Physical Description:
1 online resource (xv, 301 pages) : illustrations, diagrams.
Series:
Advances in clinical chemistry ; 39
Advances in Clinical Chemistry.
Contents:
Front Cover -- Advances in Clinical Chemistry -- Copyright Page -- Contents -- Contributors -- Preface -- Chapter 1. Clinical and Analytical Review of Ischemia-Modified Albumin Measured by the Albumin Cobalt Binding Test -- 1. Introduction -- 2. IMA and the ACB Test -- 3. Clinical Studies Review -- 4. Future Needs and Unanswered Questions -- 5. Summary -- References -- Chapter 2. Human Tissue Kallikreins: From Gene Structure to Function and Clinical Applications -- 1. Introduction.
2. Discovery of the Human Tissue Kallikrein Gene Locus: A Short Historical Perspective -- 3. Kallikreins in Rodents and Other Species -- 4. Characterization and Sequence Analysis of the Human Tissue Kallikrein Gene Locus -- 5. Structural Features of the Human Tissue Kallikrein Genes and Proteins -- 6. Sequence Variations of Human Kallikrein Genes -- 7. The Tissue Kallikreins in the Context of Other Serine Proteases in the Human Genome -- 8. Tissue Expression and Cellular Localization of the Kallikrein Genes -- 9. Regulation of Kallikrein Activity.
10. Hormonal Regulation of Kallikreins -- 11. Evolution of Kallikreins -- 12. Cross-Talk Between Kallikreins: A Possible Novel Enzymatic Cascade Pathway -- 13. Isoforms and Splice Variants of the Human Kallikreins -- 14. Kallikreins in Normal Physiology -- 15. Association of Kallikreins with Human Diseases -- 16. Kallikreins and Cancer -- 17. Therapeutic Applications -- 18. Future Directions -- References -- Chapter 3. Cholesterol and Lipids in Depression: Stress, Hypothalamo-Pituitary-Adrenocortical Axis, and Inflammation/Immunity -- 1. Introduction.
2. The Relationships Between Lipid Profile Levels, Depression, and Suicide Attempts -- 3. The Interactions Between Stress, Lipid Profiles, Cortisone/HPA Axis, and Inflammation/Immunity -- 4. Clinical Phenotypes in Depression and Molecular Levels -- 5. Conclusion -- References -- Chapter 4. Advances on Biological Markers in Early Diagnosis of Alzheimer Disease -- 1. Introduction -- 2. Biological Aspects of AD Pathogenesis -- 3. Diagnostic Issues -- 4. Biological Markers and Early Diagnosis of AD -- 5. CSF Biomarkers -- 6. Peripheral Biomarkers.
7. Future Approaches in Preclinical Diagnosis of AD -- 8. Conclusive Remarks -- References -- Chapter 5. Endothelial Microparticles (EMP) as Vascular Disease Markers -- 1. Introduction -- 2. Characterization of EMPs -- 3. Methodology to Detect EMP -- 4. EMPs in Clinical Disease -- 5. Perspective -- References -- Chapter 6. Proteomics in Clinical Laboratory Diagnosis -- 1. Introduction to Proteomics -- 2. Modern Proteomic Technology -- 3. Proteins, Proteomics, and Patterns -- 4. Accessing Biological Samples.
Abstract:
Volume thirty-nine in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general. *Presents advances in assay methods such as immuno-PCR technology and proteomic assessment *Discusses the development and potential applications of novel biomarkers of chronic conditions (i.e, . Alzheimer's disease, cancer, cardiovascular disease and depression) *Addresses molecular and biochemical findings in the aging process.
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Electronic Access:
ScienceDirect http://www.sciencedirect.com/science/book/9780120103393Available:*
Shelf Number | Item Barcode | Shelf Location | Status |
|---|---|---|---|
| RB1 .A2 2005 EB | 1180810-1001 | Elsevier E-Book Collections | Searching... |
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