Cover; Contents; Editor's Preface; Volume 41-Advances in Physical Organic Chemistry; Contributors to Volume 41; The interpretation and mechanistic significance of activation volumes for organometallic reactions; Introduction: basic principles and theory; Experimental; Volumes of activation for thermal organometallic reactions; Volumes of activation for radiation-induced organometallic reactions; Concluding remarks; Acknowledgements; References; Kinetic and mechanistic studies of the reactivity of Zn-OHn (n = 1 or 2) species in small molecule analogs of zinc-containing metalloenzymes

Pyranosyl oxocarbenium ion conformations and reactivityComputational analyses of oxocarbenium ion reactions; Mechanistic studies of ''synthetic'' reactions and glycon donors; Experimental gas-phase studies; Conclusions; Acknowledgments; References; Effect of enzyme dynamics on catalytic activity; Introduction; Proton transfer and rate-promoting vibrations; Examples of rate-promoting motions in enzymatic systems; Description in atomic detail of correlated protein motions; Conformational fluctuations; References; Cumulative Index of Authors; Cumulative Index of Titles; Subject Index