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Physical forces and the mammalian cell
Title:
Physical forces and the mammalian cell
Author:
Frangos, John A.
ISBN:
9780323140195
Publication Information:
San Diego : Academic Press, ©1993.
Physical Description:
1 online resource (xv, 400 pages) : illustrations
Contents:
Techniques for studying the effects of physical forces on mammalian cells and measuring cell mechanical properties / Roger Tran-Son-Tay -- Mechanochemical transduction across extracellular matrix and through the cytoskeleton / Donald Ingber [and others] -- Mechanical strain and the mammalian cell / Albert J. Banes -- Hemodynamic forces in relation to mechanosensitive ion channels in endothelial cells / Peter F. Davies and Randal O. Dull -- Effects of flow on anchorage-dependent mammalian cells: secreted products / Francois Berthiaume and John A. Frangos -- Shear stress effects on the morphology and cytomatrix of cultured vascular endothelial cells / Peggy R. Girard, Gabriel Helmlinger and Robert M. Nerem -- Fluid shear-stress-dependent stimulation of endothelial autacoid release: mechanisms and significance for the control of vascular tone / Rudi Busse and Ulrich Pohl -- Chronic effects of blood flow on the artery wall / B. Lowell Langille -- Fluid stress effects on suspended cells / Larry V. McIntire and Sridhar Rajagopalan.
(cont) Physical forces in mammalian cell bioreactors / Eleftherios T. Papoutsakis and James D. Michaels -- Gravity and the mammalian cell / Paul Todd.
Abstract:
This book examines the physical forces - fluid shear, stretch, and gravity that play a role in the physiology of tissues and cellular functions. It gives special attention to the influences of the flow of blood and exercise on the growth of blood vessels and the flow of interstitial fluid on bone formation. Pathological conditions are also presented, such as the lack of mechanical loading on bone and osteoporosis. For biotechnologists, the problem of cell susceptibility to agitation-induced hydrodynamic forces in the scale-up of mammalian cell bioreactors is examined.
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Electronic Access:
ScienceDirect https://www.sciencedirect.com/science/book/9780122653308Available:*
Shelf Number | Item Barcode | Shelf Location | Status |
|---|---|---|---|
| QH505 .P46 1993 | 1182192-1001 | Elsevier E-Book Collections | Searching... |
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