Front cover; Volume Two Eighty Three: International Review of Cell and Molecular Biology; Copyright page; Contents; Contributors; Chapter 1: Use of Virtual Cell in Studies of Cellular Dynamics; Abstract; 1. Introduction; 2. Modeling Capabilities of VCell; 3. What One Can Accomplish with the VCell (Review of Published Studies); 4. Future Directions in Developing Tools for Modeling in Cell Biology; Acknowledgments; References; Chapter 2: New Insights into the Dynamics of Cell Adhesions; Abstract; 1. Introduction; 2. Overview of Cell Adhesion; 3. Overview of Cell-Adhesion Proteins.

4. Regulation of Cell Adhesion Dynamics In Vitro5. Regulation of Cell-Adhesion Dynamics: In Vivo Studies; 6. Conclusions and Future Directions; References; Chapter 3: Axonal Ensheathment and Intercellular Barrier Formation in Drosophila; Abstract; 1. Introduction; 2. Drosophila Axonal Ensheathment and Vertebrate Myelination; 3. Axonal Ensheathment in the Drosophila PNS; 4. Axonal Ensheathment in Drosophila CNS; 5. BBB Formation in Drosophila; 6. Concluding Remarks; Acknowledgments; References; Chapter 4: Making Senses: Development of Vertebrate Cranial Placodes; Abstract.

1. Introduction: A Diversity of Placodes2. The Panplacodal Primordium: A Common Region of Origin for all Placodes; 3. Induction and Specification of the Panplacodal Primordium; 4. Regionalization of the Panplacodal Primordium and Development of Individual Placodes; 5. Specification and Differentiation of Placodal Neurons and Sensory Cells; 6. Morphogenesis of Placodes; 7. Conclusions; Acknowledgments; References; Chapter 5: Mechanisms of Protein Kinase A Anchoring; Abstract; 1. Introduction; 2. Proteins Involved in Compartmentalized cAMP/PKA Signaling; 3. AKAPs: Scaffolds for Local Signaling.

4. Cellular Functions Regulated by AKAP-Anchored PKA5. AKAP Dysfunction in Human Disease; 6. Concluding Remarks; Acknowledgments; References; Index; Colour plate.