PART I. Optical Biosensors: The Present -- Chapter 1. Optrode-based Fiber Optic Biosensors -- Israel Biran and David R. Walt -- Chapter 2. Evanescent Wave Fiber Optic Biosensors -- Chris Rowe Taitt and Frances S. Ligler -- Chapter 3. Planar Waveguides for Fluorescence Biosensors -- Kim Sapsford, Chris Rowe Taitt, and Frances S. Ligler -- Chapter 4. Flow Immnosensor -- Anne W. Kusterbeck -- Chapter 5. Time Resolved Fluorescence -- Richard Thompson -- Chapter 6. Electrochemiluminescence -- Mark M. Richter -- Chapter 7. Surface Plasmon Resonance Biosensors -- Jiri Homola, Sinclair Yee, and David Myszka -- Chapter 8. The Resonant Mirror Optical Biosensor -- Tim Kinning and Paul Edwards -- Chapter 9. Interferometric Biosensors -- Daniel P. Campbell and Candice J. McCloskey -- Part II. Optical Biosensors: The Future -- Chapter 10. Genetic Engineering of Signaling Molecules -- Agatha Feltus and Sylvia Daunert -- Chapter 11. Artificial Receptors for Chemosensors -- Thomas W. Bell and Nicholas M. Hext -- Chapter 12. Nucleic Acids for Reagentless Biosensors -- Manjula Rajendran and Andrew D. Ellington -- Chapter 13. New Materials Based on Imprinted Polymers and -- Their Application in Optical Sensors -- Sergey Piletsky and Anthony P.F. Turner -- Chapter 14. Optically Based Sol-Gell Biosensor Materials -- Jenna L. Rickus, Bruce Dunn, and Jeffrey I. Zink -- Chapter 15. Membrane-based Biosensors -- Bruce Corell -- Chapter 16. Pebble Nanosensors for Real Time Intracellular -- Chemical Imaging -- Murphy Brasuel, Raoul Kopelman, Martin A. Philbert, -- Jonathan W. Aylott, Heather Clark, Ilana Kasman, Matthew -- King, Eric Monson, James Sumner, Hao Xu, Marion Hoyer, -- Terry J. Miller and Ron Tjalkens -- Chapter 17. Colloidal Semiconductor Quantum Dot Conjugates in Biosensing -- Hedi Mattousssi, M. Kenneth Kuno, Ellen R. Goldman, -- George P. Anderson, and J. Matthew Mauro -- Chapter 18. Soft Lithography and Microfluidics -- Ravi S. Kane, Abraham D. Stroock, Noo Li Jeon, Donald E. -- Ingber, and George M. Whitesides -- Index.