Introductory Remarks: Adenosine A2A Receptor Antagonists: A Novel Approach to the Treatment of Parkinson's Disease. / Localisation of Adenosine Receptors in Brain and Periphery. / Medicinal Chemistry of Adenosine Receptors in Brain and Periphery. / Overview of the Physiology and Pharmacology of Adenosine in the Peripheral System. / Biochemical Characterization of Adenosine Agonists and Antagonists. / Physiology of Adenosine Receptors in the Striatum: Regulation of Striatal Projection Neurons. / The Regulation of Neurotransmitter Release in Basal Ganglia by Adenosine Receptor Agonists and Antagonists in Vitro and in Vivo. / Control of Gene Expression in the Basal Ganglia Induced by Adenosine Receptors. / Knockout Mice in the Study of Dopaminergic Diseases. / Effects of Adenosine Receptors Experimental Models of Cognition and Motor Behaviour. / Actions of Adenosine Antagonists in a Primate Model of Parkinson's Disease. / Selective Adenosine A2A Receptor Antagonism as an Alternative Therapy for Parkinson's Disease: A Study in Nonhuman Primates. / Neurobiology of Adenosine Receptors: Adenosine and its Metabolites in Movement Disorders.