Front Cover; Advances in Pharmacology and Chemotherapy, Volume 7; Copyright Page; Contents; Contributors to This Volume; Foreword; Preface; Chapter 1. Recent Progress in Pharmacogenetics; I. History; II. Definitions; III. Types of Response to Drugs; IV. Genetic Control of Drug Elimination from Human Plasma; V. Genetic Conditions, Probably Transmitted as Single Factors, Altering the Way the Body Acts on Drugs; VI. Genetic Conditions, Probably Transmitted as Single Factors, Altering the Way Drugs Act on the Body; VII. Conclusion; References

Chapter 2. The Combination of Gas Chromatography and Mass Spectrometry in the Identification of Drugs and MetabolitesI. Introduction; II. Principles of Combined Gas Chromatography-Mass Spectrometry (GC-MS); III. Applications of Combined Gas Chromatography-Mass Spectrometry (GS-MS); IV. Conclusions; References; Chapter 3. Drugs and the Mechanism of Insulin Secretion; I. Introduction; II. Glucose, Hexoses, and Pentitols; III. Fatty Acids and Ketone Bodies; IV. Enteroinsular Axis; V. Amino Acids; VI. Glucagon; VII. Tolbutamide; VIII. Other Hormones; IX. Pharmacologic Agents

X. Insulin Synthesis and StorageXI. Cations; XII. Cyclic 3',5 '-AMP; XIII. ß-Cell Secretion Hypothesis; References; Chapter 4. Antineoplastic Principles in Plants: Recent Developments in the Field; I. Introduction; II. Scope of the Present Report; III. Classes of Active Agents; IV. Plants Showing Antitumor Activity but no Longer of Interest; V. Conclusions; References; Chapter 5. The Evaluation of Present Antileprosy Compounds; I. Introduction; II. Experimental Evaluation of Drugs; III. Controlled Clinical Trials; IV. Modern Standard Therapy; V. Relapse in Leprosy; VI. Drug Resistance

VII. Drugs Used in Acute Exacerbation of Lepromatous LeprosyVIII. Prophylaxis; IX. The Way Ahead; References; Chapter 6. Chemotherapy of Chlamydial Infections; I. Introduction : Biological Characteristics of Chlamydiae-Types of Clinical Disease; II. Action of Antimicrobial Drugs on Chlamydiae in Experimental Models; III. Psittacosis and Ornithosis: Natural Infection in Birds; IV. Psittacosis in Man; V. Lymphogranuloma Venereum (LGV); VI. Trachoma-Inclusion Conjunctivitis (TRIC); VII. Summary; References; Chapter 7. Composition of Bacterial Cell Walls in Relation to Antibiotic Action

I. IntroductionII. Murein Biosynthesis; III. Connection between Antibiotic Action and Murein Synthesis; IV. Antibiotic Action and Murein Breakdown; V. Conclusion; References; Chapter 8. Advances in the Chemotherapy of Viral Diseases; I. Introduction; II. The Current Status of the Chemotherapy of Viral Diseases; III. The Reasons for the Limited Progress Made to Date and Suggestions for Improved Approaches; IV. The Future of the Chemotherapy of Viral Diseases; V. Conclusions; References; Chapter 9. A Pharmacological Analysis of Aspirin; I. Introduction; II. Antipyresis; III. Antinociception