Front Cover; Progress in Nucleic Acid Research and Molecular Biology, Volume 47; Copyright Page; Contents; Abbreviations and Symbols; Some Articles Planned for Future Volumes; Chapter 1. Prestalk Cell-differentiation and Movement during the Morphogenesis of Dictyostelium discoideum; I. Extracellular cAMP-signaling in Dictyostelium; II. Cellular Differentiation and the Role of Differentiation-inducing Factor; III. Prestalk Cell Heterogeneity; IV. Slug Formation; V. Culmination; VI. Intracellular Signaling and the Multiple Roles of cAMP-dependent Protein Kinase

IV. The tis10 Gene Encodes a Functional Prostaglandin Synthase/CyclooxygenaseV. Both Prostaglandin Synthesis and TlS10/PGS-2 Synthesis Are Induced in Swiss 3T3 Cells; VI. The Structures of the tis10/pgs-2 and pgs-1 Genes Are Similar; VII. tis10/pgs-2 Satisfies the Criteria for the ""Second Pool"" of Prostaglandin Synthase; VIII. tis10/pgs-2 Is Induced in Macrophages; IX. Can the Proteins Encoded by the tis10/pgs-2 and pgs-1 Genes Form Functional Heterodimers? What Would Be the Consequences of This Interaction for Pharmacologic Intervention?

X. Similarities in the Expression and Regulation of Inducible Forms of Prostaglandin Synthase and Nitric-Oxide SynthaseXI. Conclusions and Future Directions; References; Chapter 5. Nuclear Pre-mRNA Processing in Higher Plants; I. Biochemistry of Splicing and lntron Recognition; II. Plant Splicing; III. Transposable-element-induced Mutants of Maize; IV. Examples of Alternative Splicing; V. Biological Phenomena Associated with Splicing; VI. Perspective; References; Chapter 6. New Concepts in Protein-DNA Recognition: Sequence-directed DNA Bending and Flexibility