PART I  Delivery and Pain.- Gonadal Hormones and Pain Modulation -- Stress and Pregnancy: CRF as Biochemical Marker.-  Pain Control During Labour.- PART II Fetal Pain.- Ultrasound and Fetal Stress: Study of the Fetal Blink-Startle Reflex Evoked by Acoustic Stimuli.- Prenatal Affective Exchanges and Their Subsequent Effects in Postnatal Life.- Pain in the Fetus.- New Insights into Prenatal Stress: Immediate and Long-Term Effects on the Fetus and Their Timing.- PART III Neonatal Pain.- Pain Assessment and Spectral Analysis of Neonatal Crying.- Analgesic Procedures in Newborns.- Nonpharmacological Treatment of Neonatal Pain.- Sensory Saturation: An Analgesic Method.- Pharmacologic Analgesia in the Newborn.- Physical Stress Risk Agents in Incubators.- Fetal surgery analgesia.- PART IV Pain: a Risk Factor for Brain Damage.- Neonatal Stressors -- New Insights into Neonatal Hypersensitivity.- From the Gate-Control Theory to Brain Programs for Neonatal Pain.- PART V Pain and Communication.- Disclosure of Pathology to the Newborn’s Family.- Communication of Diagnosis: Pain and Grief in the Experience of  Parents of Children with a Congenital Malformation.- Invest in Prenatal Life: A High-Yield Stock.