Synthesis and characterisation of block copolymers of poly(ethylene oxide-block-styrene oxide) for the enhancement of drug solubility

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Title:

Synthesis and characterisation of block copolymers of poly(ethylene oxide-block-styrene oxide) for the enhancement of drug solubility

Author:

Crothers, Michael E. D., author.

ISBN:

9780355978339

Personal Author:

Crothers, Michael E. D., author.

Physical Description:

1 electronic resource (213 pages)

General Note:

Source: Dissertation Abstracts International, Volume: 76-08C.

Abstract:

Three triblock copolymers, E65S11E65, E66S13E66 and E67S15E67, and four diblock copolymers S15E63, S17E65, S20E67 and E17S8 (where E denotes an ethylene oxide unit and S denotes a styrene oxide unit) have been synthesised by sequential anionic copolymerisation using high vacuum and ampoule techniques. 13C nuclear magnetic resonance spectroscopy was used to determine the number averaged block lengths. Analysis by gel permeation chromatography showed that the individual blocks and the overall copolymer had narrow molar mass distributions (Mw/Mn

Local Note:

School code: 1543

Subject Term:

Pharmacology.

Polymer chemistry.

Added Corporate Author:

The University of Manchester (United Kingdom). School of Pharmacy and Pharmaceutical Sciences.

Electronic Access:

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10836286

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Shelf Number	Item Barcode	Shelf Location	Status
XX(683869.1)	683869-1001	Proquest E-Thesis Collection	Searching...

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