Burnout has been found to be a widespread occurrence throughout all workplace environments. Although research regarding burnout does exist, there is limited research focusing on direct patient-care staff working with forensic populations. A quantitative research design was developed to assess burnout levels among 100 direct patient-care staff serving a forensic population. An independent samples t-test was conducted to examine gender differences for total burnout scores. It was hypothesized that females would report higher levels of burnout in comparison to male counterparts. Results revealed a significant between group difference by gender. A linear regression was conducted to examine the extent to which years of employment predicted burnout. It was hypothesized that longer length of employment would predict higher levels of burnout. Results were not statistically significant. A one-way multivariate analysis of variance (MANOVA) was conducted to examine gender differences in anger, frustration, and emotional drain related to the work environment. It was hypothesized that males would report more anger in comparison to females, whereas, females would report higher levels of emotional drain and frustration in comparison to male counterparts. Results were not significant. Burnout affects all professionals across all work place. For this reason, it is important to take necessary precautions within all work environments.