Select an Action
Development of a Focused Library of C2 and C5 Modified 4-Chromanone Derivatives as Potential Antimicrobials
Title:
Development of a Focused Library of C2 and C5 Modified 4-Chromanone Derivatives as Potential Antimicrobials
Author:
Cusack, Michael, author.
ISBN:
9780438008113
Personal Author:
Physical Description:
1 electronic resource (82 pages)
General Note:
Source: Masters Abstracts International, Volume: 57-06M(E).
Advisors: Marcelo Nieto Committee members: Mike Crider; Sarah Luesse.
Abstract:
A focused library of seven C2 and C5 modified 4- chromanones derivatives was generated by classical lineal synthesis, and tested for antimicrobial activity. The C2 and the C5 positions were derivatized with alkyl and spiro ketones, and a primary amine and benzenesulfonamides, respectively. For the C2 position, the dimethyl, and cyclohexyl derivatives were found to be mildly active (up to MIC = 256 mug/mL). In regards to the C5 position, the amine derivatives were found to have mild activity (up to MIC = 256 mug/mL) against Staphylococcus aureus (ATCC 29213) and the Nbenzenesulfonyl derivatives showed mild activity against Escherichia coli (ATCC 25922).
Local Note:
School code: 0509
Added Corporate Author:
Available:*
Shelf Number | Item Barcode | Shelf Location | Status |
|---|---|---|---|
| XX(691361.1) | 691361-1001 | Proquest E-Thesis Collection | Searching... |
On Order
Select a list
Make this your default list.
The following items were successfully added.
There was an error while adding the following items. Please try again.
:
Select An Item
Data usage warning: You will receive one text message for each title you selected.
Standard text messaging rates apply.