This thesis presents the work conducted during a three year research project in the field of Control Systems and Biomaterials Engineering. The findings are presented over seven chapters, starting with a thorough literature review of the existing methods and key technologies, and following through by highlighting the existing problems with the current methods and how they have been overcome. The data is presented in tables, figures and photographs to enhance understanding and clarification. The research focuses on two relatively new manufacturing methods in the field of Tissue Engineering. Both of the methods are used for creating materials for regeneration of human and animal tissue, with the aim of replacing the current surgical methods. The methods are viewed from a control systems perspective and improvements have been made with the implementation of new technologies and methods. Additionally, further advancements are presented on the theoretical modelling field of control systems, where the shortfalls of existent modelling methods are highlighted and solutions proposed.