Front Cover; Antibody Production in Man: In Vitro Synthesis and Clinical Implications; Copyright Page; Table of Contents; CONTRIBUTORS; PREFACE; CHAPTER 1. CONSIDERATION OF ANTIBODY DEFICIENCY DISEASES IN RELATION TO NORMAL B-CELL DEVELOPMENT; I. NORMAL DEVELOPMENT OF B CELLS; II. CONCLUSION; REFERENCES; CHAPTER 2. POKEWEED MITOGEN-INDUCED PFC RESPONSES OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES: REGULATION OF B-CELL TRIGGERING; I. INTRODUCTION; II. MATERIALS AND METHODS; III. RESULTS; IV. DISCUSSION; V. SUMMARY; REFERENCES

CHAPTER 3. INDUCTION OF ANTIBODY SYNTHESIS IN HUMAN LYMPHOCYTES FROM DIFFERENT ORGANS BY DIFFERENT PBA SUBSTANCESI. INTRODUCTION; II. OPTIMAL CONDITIONS FOR THE INDUCTION OF POLYCLONAL ANTIBODY RESPONSE BY LPS; III. LOCALIZATION OF B CELLS RESPONDING TO DIFFERENT BACTERIAL STRAINS WITH ANTIBODY FORMATION; IV. PBA PROPERTIES OF DIFFERENT BACTERIAL PREPARATIONS; V. AGE-DEPENDENT RESPONSE TO DIFFERENT BACTERIA IN ADENOID LYMPHOCYTES; VI. POLYCLONAL B CELL RESPONSE TO PPD IN CHILDREN WITH BCG INFECTION; VII. SUMMARY; REFERENCES

CHAPTER 4. THE PLAQUE-FORMING CELL RESPONSE OF HUMAN BLOOD LYMPHOCYTES COCULTIVATION OF LYMPHOCYTES FROM DIFFERENT INDIVIDUALSI. INTRODUCTION; II. METHODS; III. RESULTS; IV. DISCUSSION; REFERENCES; PART I: GENERAL DISCUSSION MITOGEN INDUCED B CELL ACTIVATION. I.; CHAPTER 5. T-T INTERACTIONS IN THE GENERATION OF HUMAN SUPPRESSOR EFFECTOR CELLS IN VITRO; I. INTRODUCTION; II. MATERIALS AND METHODS; III. RESULTS; IV. DISCUSSION; V. SUMMARY; REFERENCES; CHAPTER 6. BIOSYNTHESIS AND SECRETION OF IMMUNOGLOBULINS BY HUMAN PERIPHERAL BLOOD LYMPHOCYTES; I. INTRODUCTION; II. MATERIALS AND METHODS

Ill. RESULTSIV. DISCUSSION; REFERENCES; CHAPTER 7. ANTIGEN SPECIFIC AND ANTIGEN NONSPECIFIC TRIGGERING OF HUMAN B LYMPHOCYTES; I. INTRODUCTION; II. MATERIAL AND METHODS; III. RESULTS; REFERENCES; PART II: GENERAL DISCUSSION MITOGEN-INDUCED B-CELL ACTIVATION. II.; CHAPTER 8. ANTIGEN-INDUCED REGULATION OF THE PFC RESPONSE IN MAN; I. INTRODUCTION; II. MATERIALS AND METHODS; III. RESULTS AND DICUSSION; IV. SUMMARY; REFERENCES; CHAPTER 9. HUMAN B-CELL ACTIVATION IN VITRO: REGULATION BY ANTIGEN-SPECIFIC HUMAN SUPPRESSOR T CELLS; I. INTRODUCTION; II. MATERIALS AND METHODS; III. RESULTS

IV. DISCUSSIONV. SUMMARY; REFERENCES; CHAPTER 10. PRIMARY IN VITRO ANTIBODY RESPONSE TO TNP-PAA : CELLULAR BASIS; I. INTRODUCTION; II. MATERIALS AND METHODS; III. RESULTS; IV. DISCUSSION; REFERENCES; PART III: GENERAL DISCUSSION ANTIGEN INDUCED B CELL ACTIVATION. I.; CHAPTER 11. T -- B COLLABORATION IN THE IN VITRO AB RESPONSE TO DIPHTHERIA TOXOID; EVIDENCE FAVOURING A ROLE FOR B CELLS IN THE GENERATION OF T CELL HELP; REFERENCES; CHAPTER 12. ANTIGEN-DEPENDENT PFC INDUCTION IN CULTURES OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES; I. INTRODUCTION