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Biology of serpins
Title:
Biology of serpins
Author:
Whisstock, James C.
ISBN:
9780123864710
Edition:
1st ed.
Publication Information:
San Diego, CA : Academic Press, 2011.
Physical Description:
1 online resource (l, 405 pages) : illustrations.
Series:
Methods in enzymology, v. 499
Methods in enzymology ; v. 499.
Contents:
Analysis of Serpin Secretion, Misfolding, and Surveillance in the Endoplasmic Reticulum -- Serpin-Enzyme Receptors: LDL Receptor-Related Protein 1 -- The Role of Autophagy in Alpha-1-Antitrypsin Deficiency -- Serpins and the Complement System -- Use of Mouse Models to Study Plasminogen Activator Inhibitor-1 -- Plasminogen Activator Inhibitor Type 2: Still an Enigmatic Serpin but a Model for Gene Regulation -- The SerpinB1 Knockout Mouse: A Model for Studying Neutrophil Protease Regulation in Homeostasis and Inflammation -- Investigating Maspin in Breast Cancer Progression Using Mouse Models -- Hsp47 as a collagen-specific molecular chaperone -- Assays for the Antiangiogenic and Neurotrophic Serpin Pigment Epithelium-Derived Factor -- The Drosophila Serpins: Multiple Functions in Immunity and Morphogenesis -- Modeling Serpin Conformational Diseases in Drosophila melanogaster -- Using Caenorhabditis elegans to Study Serpinopathies -- Using C. elegans to Identify the Protease Targets of Serpins In Vivo -- Viral Serpin Therapeutics: From Concept to Clinic -- man SCCA Serpins Inhibit Staphylococcal Cysteine Proteases by Forming Classic "Serpin-Like' Covalent Complexes -- Plants and the Study of Serpin Biology.
Abstract:
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.
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Electronic Access:
ScienceDirect eBooks ScienceDirect http://www.sciencedirect.com/science/book/9780123864710 ScienceDirect http://www.sciencedirect.com/science/bookseries/00766879/499Available:*
Shelf Number | Item Barcode | Shelf Location | Status |
|---|---|---|---|
| QP601 .M49 V.499 | 1183428-1001 | Elsevier E-Book Collections | Searching... |
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