Front Cover -- Advances in Cancer Research, Volume 39 -- Copyright Page -- Contents -- Contributors to Volume 39 -- Chapter 1. Neoplastic Development in Airway Epithelium -- I. Introduction -- II. Experimental Approaches and Methodologies -- III. Morphology of Acute Phase Responses-Early Induction Phase -- IV. Chronic Phase Responses -- V. Cell Population Studies during Neoplastic Development -- VI. Modifiers of Neoplastic Development in Airway Epithelium -- VII. Conclusions -- References -- Chapter 2. Concomitant Tumor Immunity and the Resistance to a Second Tumor Challenge.

I. Introduction -- II. Tumor Excision and Resistance to a Second Tumor Challenge: Sinecomitant Immunity -- III. Resistance of the Tumor-Bearing Host to a Second Tumor Challenge: Concomitant Tumor Immunity -- IV. Metastases as a Second Tumor Graft: Antimetastatic Concomitant Immunity -- V. Is the Status of Concomitant Immunity Unique for a Tumor-Host Relationship? -- VI. Mechanisms of Resistance of the Tumor-Rearing Host to a Second Tumor Graft -- VII. Mechanisms of the Inhibition of Metastases Development by the Primary Tumor -- VIII. Conclusion and Summary -- References.

Chapter 3. Antigenic Tumor Cell Variants Obtained with Mutagens -- I. Introduction -- II. Evidence for the Production of Tumor Cells with Increased Immunogenicity by Mutagen Treatment -- III. Immunogenic Variants Obtained in Vitro with Nitrosoguanidine Derivative MNNG -- IV. Immunogenic Tumor Cell Populations Obtained in Vivo with Triazenylimidazole Derivative DTIC -- V. Discussion -- References -- Chapter 4. Chromosomes and Cancer in the Mouse: Studies in Tumors Established Cell Lines, and Cell Hybrids -- I. Introduction -- II. T-Cell Leukemias -- III. B-Cell Leukemias -- IV. Plasmacytomas.

V. Evidence from Cell Lines for the Role of Chromosome 15 -- VI. Viruses and Genes Related to Tumorigenesis -- VII. Do All Tumors Have Specific Chromosome Changes? -- VIII. Gene Amplification: Homogeneously Staining Regions and Double Minute Chromosomes -- IX. General Characteristics of Mouse Cell Lines -- X. Suppression of Tumorigenicity in Hybrid Cells -- XI. Chromosome Loss in Tumorigenic Hybrids -- XII. Chromosome 4, in Vitro Growth and Tumorigenicity -- XIII. Complementation Analysis and the Number of Genes Involved in Tumorigenicity -- XIV. Trisomy 15 in Tumorigenic Hybrids.

XV. Suppression of Tumorigenicity by DNA Fragments -- XVI. SV40-Induced Transformation and Tumorigenicity in Hybrid Cells -- XVII. Common Mechanisms of Tumor Suppression in Interspecific Hybrids -- XVIII. Genetic Basis of Transformation and Tumorigenicity -- XIX. Altered Hexose Transport in Malignant Cells -- XX. Host Cell Recruitment into Tumors via Cell Fusion -- XXI. Conclusions -- References -- Chapter 5. Polyomavirus: An Overview of Its Unique Properties -- I. Introduction -- II. Background -- III. Structural Organization of the Viral Genome.