Front Cover -- Advances in Cancer Research, Volume 42 -- Copyright Page -- Contents -- Contributors to Volumes 42 -- Chapter 1. Immunological Surveillance of Tumors in the Context of Major Histocompatibility Complex Restriction of T Cell Function -- I. Introduction -- II. Immunological Surveillance: Historical Aspects and Early Speculations Concerning Transplantation Antigens -- III. Criticisms of Immunological Surveillance 1970 -- IV. Evidence That T Cell Surveillance Is Important in Some Tumor Systems -- V. MHC-Restricted T Cell Recognition -- VI. The Molecular Nature of the MHC.

VII. T Lymphocyte Effectors and Tumor-Specific Transplantation Antigens -- VIII. Biological Models for Recognition of Minimal Changes on Cell Surface: T Cell Responses to SV40 TSTA and Single Minor H Antigens -- IX. The Expression of MHC Antigens on Tumor Cells -- X. MHC Phenotype and Susceptibility to Cancer -- XI. General Concepts -- XII. Summary -- References -- Chapter 2. lmmunohistological Analysis of Human Lymphoma: Correlation of Histological and Immunological Categories -- I. Introduction -- II. Distinction of Malignant Lymphoma from Other Neoplasms.

III. Division of Malignant Lymphoma into Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, and True Histiocytic Sarcoma -- IV. B Cell Lymphomas -- V. T Cell Lymphomas -- VI. Conclusion -- References -- Chapter 3. Induced Differentiation of Murine Erythroleukemia Cells: Cellular and Molecular Mechanisms -- I. Introduction -- II. Terminal Cell Division -- III. Gene Expression, DNA Structure, and Chromatin Configuration during Induced Differentiation -- IV. Differentiation and the Cell Cycle -- V. Summary -- References -- Chapter 4. Protoneoplasia: The Molecular Biology of Murine Mammary Hyperplasia.

I. Introduction -- II. Mouse Mammary Tumor System -- III. The Development of Transplantable Hyperplastic Outgrowth Lines -- IV. Characterization of Hyperplastic Outgrowth Lines -- V. Restriction Endonuclease Mapping -- VI. The Molecular Biology of Mouse Mammary Neoplasia -- VII. Origin and Evolution of Mouse Mammary Tumors -- VIII. The HAN Is Protoneoplastic -- IX. The Role of MuMTV in Mouse Mammary Tumorigenesis -- X. Summary -- References -- Chapter 5. Xiphophorus as an in Vivo Model for Studies on Normal and Defective Control of Oncogenes -- I. Introduction and Historical Background.

II. Ubiquity of Oncogenes in Purebred Animals Derived from Wild Populations -- III. Defective Control of Oncogenes in Hybrids -- IV. Oncogenes and Regulatory Genes -- V. Theoretical Considerations on a General Concept of Neoplasia -- VI. Conclusions -- References -- Chapter 6. Contrasuppression: The Second Law of Thymodynamics, Revisited -- I. Introduction -- II. Defining Cell Circuits -- III. Defining Contrasuppression -- IV. Defining a Specific Contrasuppressor Circuit and Assigning a Unique Phenotype to Its Cellular and Molecular Members.