Front Cover; Advances in Immunology, Volume 5; Copyright Page; Contents; List of Contributors; Preface; Chapter 1. Natural Antibodies and the Immune Response; I. Introduction; II. Natural Antibodies and Other Components of Serum Reactive with Immunologically Inacceptable Material; III. The Occurrence of Natural Antibodies; IV. The Origin of Natural Antibodies; V. Characteristics of Natural Antibodies; VI. Natural Antibodies as Recognition Factors; References; Chapter 2. Immunological Studies with Synthetic Polypeptides; I. Introduction.

II. Synthesis and Characterization of Polyamino Acids and Polypeptidyl ProteinsIII. Antigenic Properties of Polypeptidyl Proteins; IV. Synthetic Polypeptide Antigens; V. Reactions of Synthetic Polypeptides with Antisera to Proteins; VI. Conjugates of Synthetic Polypeptides; VII. Antigenic Properties of Natural Polyglutamic Acid; VIII. Antigenicity of Some Peptides Synthesized by Stepwise Methods; IX. Immunological Unresponsiveness; X. Antibodies to Synthetic Polypeptides and Polypeptidyl Proteins; XI. Concluding Remarks; References.

Chapter 3. Experimental Allergic Encephalomyelitis and Autoimmune DiseaseI. Introduction; II. General Considerations; III. Allergic Encephalomyelitis; References; Chapter 4. The Immunology of Insulin; I. Introduction; II. Insulin Antibodies in Man and Their Association with Globulin Proteins; III. Insulin Antibody Production in Animals; IV. Properties of Insulin Antibodies; V. Immunoassay Methods for Insulin; VI. Applications of Immunoassay Methods; VII. Isoantibodies and Autoimmunity to Insulin; VIII. Neutralizable and Nonneutralizable Insulin; References; Chapter 5. Tissue-Specific Antigens.

I. IntroductionII. Tissue-Specific Antigens; III. Tissue-Specific Heterophile Antigens; IV. Immune Response to Tissue-Specific Antigens; V. Physiology and Pathology of Tissue-Specific Antigens; VI. Conclusions; References; Author Index; Subject Index.