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Ex Vivo Engineering of the Tumor Microenvironment
Title:
Ex Vivo Engineering of the Tumor Microenvironment
Author:
Aref, Amir R. editor.
ISBN:
9783319453972
Physical Description:
IX, 135 p. 18 illus., 17 illus. in color. online resource.
Series:
Cancer Drug Discovery and Development,
Contents:
1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy. .
Abstract:
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
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Electronic Access:
http://dx.doi.org/10.1007/978-3-319-45397-2Available:*
Shelf Number | Item Barcode | Shelf Location | Status |
|---|---|---|---|
| RC261 -271 | 480594-1001 | SPRINGER | Searching... |
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