Between 2003 and 2015, more than 61% of U.S. software development teams failed to satisfy project requirements, budgets, or timelines. Failed projects cost the software industry an estimated 60 billion dollars. Lost opportunities and misused resources are often the result of software development leaders failing to implement appropriate methods for managing software projects. The purpose of this qualitative multiple case study was to explore strategies software development managers use in adopting Agile methodology in the context of distributed teams. The tenets of Agile approach are individual interaction over tools, working software over documentation, and collaboration over a contract. The conceptual framework for the study was adapting Agile development methodologies. The targeted population was software development managers of U.S.-based companies located in Northern California who had successfully adopted Agile methods for distributed teams. Data were collected through face-to-face interviews with 5 managers and a review of project-tracking documentation and tools. Data analysis included inductive coding of transcribed interviews and evaluation of secondary data to identify themes through methodological triangulation. Findings indicated that coaching and training of teams, incremental implementation of Agile processes, and proactive management of communication effectiveness are effective strategies for adopting Agile methodology in the context of distributed teams. Improving the efficacy of Agile adoption may translate to increased financial stability for software engineers across the world as well as accelerate the successful development of information systems, thereby enriching human lives.