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Massachusetts Institute of Technology. degree granting institution.

(2)

Abou-Fadel, Johnathan Salim, author.

(1)

Brophy, Jennifer Ann Noelani, author.

(1)

Coffey, Alisha Renee, author.

(1)

Cornell University. Chemistry & Chemical Biology. degree granting institution.

(1)

Dancy, Jimena Guadalupe, author.

(1)

Fernandez, Wadie Daniel Mahauad, author.

(1)

Goode, Kourtney M., author.

(1)

McKay, Ryan, author.

(1)

Morehouse School of Medicine. Graduate Education in Biomedical Sciences. degree granting institution.

(1)

Negrón Abril, Yashira L., author.

(1)

Northern Arizona University. Department of Biological Sciences. degree granting institution.

(1)

Princeton University. Molecular Biology. degree granting institution.

(1)

Purdue University. Medicinal Chemistry and Molecular Pharmacology. degree granting institution.

(1)

Rowland, Elizabeth Ann, author.

(1)

Stone, Nathan E., author.

(1)

Thai, Kevin K., author.

(1)

The University of Iowa. Molecular & Cell Biology. degree granting institution.

(1)

The University of North Carolina at Chapel Hill. Genetics and Molecular Biology. degree granting institution.

(1)

The University of Texas at El Paso. Biological Sciences. degree granting institution.

(1)

University of Maryland, Baltimore. Molecular Medicine. degree granting institution.

(1)

University of Maryland, College Park. Bioengineering. degree granting institution.

(1)

Wallace, LaShanale, author.

(1)

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(12)

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Subject

Molecular biology.

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Bioengineering.

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Bioinformatics.

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Biomedical engineering.

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Cellular biology.

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Nanotechnology.

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Pharmaceutical sciences.

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Library

Başkent Library

Shelf Location

Proquest E-Thesis Collection

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Cover image for AGO2 overexpression exhibits oncogenic functions in Kras G12D-associated mouse tumor models

AGO2 overexpression exhibits oncogenic functions in Kras G12D-associated mouse tumor models

1.

AGO2 overexpression exhibits oncogenic functions in Kras G12D-associated mouse tumor models

by

Thai, Kevin K., author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10903600

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tumor initiation and progression is imperative in the development of targeted therapeutics. This thesis

Cover image for Synthetic Biology Approaches for Engineering Diverse Bacterial Species

Synthetic Biology Approaches for Engineering Diverse Bacterial Species

2.

Synthetic Biology Approaches for Engineering Diverse Bacterial Species

by

Brophy, Jennifer Ann Noelani, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10902883

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Excerpt:

When engineers control gene expression, cells can be re-programmed to create living therapeutics or

Cover image for Fn14-targeted, Tissue-penetrating Nanoparticles for Treatment of Primary and Metastatic Tumors

Fn14-targeted, Tissue-penetrating Nanoparticles for Treatment of Primary and Metastatic Tumors

3.

Fn14-targeted, Tissue-penetrating Nanoparticles for Treatment of Primary and Metastatic Tumors

by

Dancy, Jimena Guadalupe, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10793804

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Excerpt:

contribute to positive disease outcomes. However, while targeting therapeutics to specific disease components

Cover image for Delineation of Mitochondrial Genome Expression in Colorectal Adenoma Progression

Delineation of Mitochondrial Genome Expression in Colorectal Adenoma Progression

4.

Delineation of Mitochondrial Genome Expression in Colorectal Adenoma Progression

by

Wallace, LaShanale, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10813074

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Excerpt:

target for CRC biomarker discovery and novel therapeutics.

Cover image for Systems Genetics Approach to Defining Genetic and MicroRNA Association with Diet-Associated Atherosclerosis

Systems Genetics Approach to Defining Genetic and MicroRNA Association with Diet-Associated Atherosclerosis

5.

Systems Genetics Approach to Defining Genetic and MicroRNA Association with Diet-Associated Atherosclerosis

by

Coffey, Alisha Renee, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10746390

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Excerpt:

necessary to identify candidates for more effective therapeutics.

Cover image for Sirtuin-regulated Lipoylation Is an Evolutionarily Conserved Mediator of Metabolic Health and Disease

Sirtuin-regulated Lipoylation Is an Evolutionarily Conserved Mediator of Metabolic Health and Disease

6.

Sirtuin-regulated Lipoylation Is an Evolutionarily Conserved Mediator of Metabolic Health and Disease

by

Rowland, Elizabeth Ann, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10787633

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Excerpt:

metabolic complexes when studying disease or developing therapeutics.

Cover image for Genetically engineered probiotics for diagnostics and drug delivery: applications for crohn’s disease

Genetically engineered probiotics for diagnostics and drug delivery: applications for crohn’s disease

7.

Genetically engineered probiotics for diagnostics and drug delivery: applications for crohn’s disease

by

McKay, Ryan, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10787036

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, and ultimately synthesize and deliver therapeutics. Nitric oxide (NO) levels are elevated at sites of

Cover image for Evidence of Asymptomatic Carriage of Toxigenic Clostridioides difficile in Canines Suggests that Components of the Gut Microbiome Provide Resistance to Disease

Evidence of Asymptomatic Carriage of Toxigenic Clostridioides difficile in Canines Suggests that Components of the Gut Microbiome Provide Resistance to Disease

8.

Evidence of Asymptomatic Carriage of Toxigenic Clostridioides difficile in Canines Suggests that Components of the Gut Microbiome Provide Resistance to Disease

by

Stone, Nathan E., author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10811684

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Excerpt:

gut could provide insights into targeted therapeutics for human CDI.

Cover image for Targeting the Hsp90 C-terminus: Development of Novel Allosteric Modulators of Chaperone Function

Targeting the Hsp90 C-terminus: Development of Novel Allosteric Modulators of Chaperone Function

9.

Targeting the Hsp90 C-terminus: Development of Novel Allosteric Modulators of Chaperone Function

by

Goode, Kourtney M., author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10268496

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Excerpt:

utility of Hsp90 targeted probes and future therapeutics.

Cover image for Steroid- CoA Ligases, FadD17A1 and FadD19A1, and Their Role in Cholesterol Side-Chain Degradation in Mycobacterium tuberculosis

Steroid- CoA Ligases, FadD17A1 and FadD19A1, and Their Role in Cholesterol Side-Chain Degradation in Mycobacterium tuberculosis

10.

Steroid- CoA Ligases, FadD17A1 and FadD19A1, and Their Role in Cholesterol Side-Chain Degradation in Mycobacterium tuberculosis

by

Abou-Fadel, Johnathan Salim, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10814786

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of ligase enzymes in this pathway for development of novel therapeutics capable of targeting the

Cover image for Tumor Promoting Functions for the Metabolic Regulator SIRT5

Tumor Promoting Functions for the Metabolic Regulator SIRT5

11.

Tumor Promoting Functions for the Metabolic Regulator SIRT5

by

Negrón Abril, Yashira L., author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10788924

Format:

Excerpt:

, we tested SIRT5-selective small molecule inhibitors as cancer therapeutics. Pharmacological

Cover image for Role of Bone Marrow Stromal Antigen 2 (BST-2) in Viral Pathogenesis and Breast Cancer Progression

Role of Bone Marrow Stromal Antigen 2 (BST-2) in Viral Pathogenesis and Breast Cancer Progression

12.

Role of Bone Marrow Stromal Antigen 2 (BST-2) in Viral Pathogenesis and Breast Cancer Progression

by

Fernandez, Wadie Daniel Mahauad, author.

http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10187431

Format:

Excerpt:

of therapeutics.

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