Viral Vectors for Treating Diseases of the Nervous System
Başlık:
Viral Vectors for Treating Diseases of the Nervous System
Yazar:
Latchman, David S., editor.
ISBN:
9780123668561
Fiziksel Tanımlama:
1 online resource (xi, 317 pages : illustrations).
Seri:
International review of neurobiology ; v. 55
International review of neurobiology ; v. 55.
İçerik:
Section I. Virus vectors for use in the central nervous system. Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders / Pedro R. Lowenstein [and others]. Adeno-associated viral vectors / E. Lehtonen and L. Tenenbaum. Problems in the use of herpes simplex virus as a vector / Lawrence T. Feldman. Lentiviral vectors / Johan Jakobsson [and others]. Retroviral vectors for gene delivery to neural precursor cells / Ryoichiro Kageyama, Hiromi Hirata, and Jun Hatakeyama -- Section II. Gene therapy with virus vectors for specific diseases of the nervous system. The principles of molecular therapies for glioblastoma / George Karpati and Josephine Nalbantoglu. Oncolytic herpes simplex virus for tumor therapy / Jennifer C.C. Hu and Robert S. Coffin. Recombinant retrovirus vectors for treatment of malignant brain tumors / Nikolai G. Rainov and Christof M. Kramm. Adeno-associated viral vectors for Parkinson's Disease / Shin-ichi Muramatsu [and others]. Herpes simplex virus vectors for Parkinson's Disease / David S. Latchman. Gene therapy for stroke / K. Abe and W.R. Zhang. Gene therapy for mucopolysaccharidosis / Assumpcio Bosch and Jean Michel Heard.
Özet:
Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. This volume describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-associated virus, Herpes Simplex Virus, lentivirus, and other retroviruses. It also discusses the potential application of such viruses in treating brain tumors, Parkinson's disease, and other diseases of the nervous system. * Provides up-to-date account of gene therapy approaches for incurable neurological disorders * Describes a range of gene delivery methods based on different viruses.
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Elektronik Erişim:
Full text - Unlimited user access. ScienceDirect http://www.sciencedirect.com/science/book/9780123668561 ScienceDirect https://www.sciencedirect.com/science/bookseries/00747742 ScienceDirect https://www.sciencedirect.com/science/book/9780123668561Mevcut:*
Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
|---|---|---|---|
| QH442.2 .V813 2003 EB | 1184351-1001 | Elsevier E-Kitap Koleksiyonu | Arıyor... |
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