Trends in drug research III : proceedings of the 13th Noordwijkerhout-Caminero [sic] Symposium, the Netherlands, 6-11 May 2001
Başlık:
Trends in drug research III : proceedings of the 13th Noordwijkerhout-Caminero [sic] Symposium, the Netherlands, 6-11 May 2001
Yazar:
Noordwijkerhout-Camerino Symposium (13th : 2001 : Noordwijkerhout, Netherlands)
ISBN:
9780444507600
9780080543239
9781281054975
9786611054977
Toplantı Adı Girişi:
Basım Bilgisi:
1st ed.
Yayın Bilgileri:
Amsterdam ; New York : Elsevier, 2002.
Fiziksel Tanımlama:
1 online resource (ix, 262 pages) : illustrations.
Seri:
Pharmacochemistry library ; v. 32
Pharmacochemistry library ; v. 32.
İçerik:
Cover -- Contents -- Preface -- Chapter 1. Towards rational design of AMPA receptor ligands: an integrated medicinal, computational, biostructural and molecular pharmacological approach -- Chapter 2. From heparin to synthetic antithrombotics. The pentasaccharide story and follow-up -- Chapter 3. A new future for synthesis? -- Chapter 4. Directed evolution of enantioselective enzymes as catalysts in the production of chiral pharmaceuticals -- Chapter 5. At the interface of organic synthesis and biosynthesis -- Chapter 6. What can structure tell us about function in the estrogen receptors? -- Chapter 7. Molecular docking and dynamics simulations in the ligand binding domain of steroid hormone receptors -- Chapter 8. Peroxisome proliferator-activated receptors and reverse endocrinology -- Chapter 9. Biomolecular mass spectrometry related to drug research -- Chapter 10. Chemical and biological diversity in drug discovery -- Chapter 11. Muscarine acetylcholine receptor knockout mice: phenotypical analysis and clinical implications -- Chapter 12. Changes in expression of the orphan G-protein coupled receptor GPR7 in human painful peripheral neuropathies -- Chapter 13. Computational methods for the analysis of molecular diversity -- Chapter 14. Enhancing drug discovery by acquisition of chemical diversity -- Chapter 15. Chemical diversity as a driving force to design and put in practice synthetic strategies leading to combinatorial libraries for lead discovery and lead optimization -- Chapter 16. Beyond G proteins: the role of accessory proteins in G protein-coupled receptor signalling -- Chapter 17. Mechanisms of action of antipsychotic drugs: the role of inverse agonism at the D2 dopamine receptor -- Chapter 18. Agonist channeling of a2-adrenoceptor function -- Chapter 19. Antibacterials as wonder drugs and how their effectiveness is being compromised -- Chapter 20. Pseudomonas aeruginosa quorum sensing: a target for antipathogenic drug discovery -- Chapter 21. Discovery and development of new anti-bacterial drugs -- Chapter 22. Discovery of small molecule insulin mimetics as potential novel antidiabetic agents -- Chapter 23. Expression databases for pharmaceutical lead optimisation -- Chapter 24. New developments in the pharmacology of cannabinoids -- Author index -- Subject index -- Last Page.
Özet:
The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and included in these proceedings, are the discoveries in green chemistry, the interface between organic synthesis and biosynthesis, the growing problem of resistant micro-organisms and the possibilities to identify new, and better, antibiotics. And finally, in recent developments, the discovery of small molecules with insulin sensitizing properties.
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Elektronik Erişim:
ScienceDirect http://www.sciencedirect.com/science/book/9780444507600 ScienceDirect http://www.sciencedirect.com/science/publication?issn=01657208&volume=32 ScienceDirect https://www.sciencedirect.com/science/publication?issn=01657208&volume=32 ScienceDirect https://www.sciencedirect.com/science/bookseries/01657208/32 ScienceDirect http://www.sciencedirect.com/science/bookseries/01657208/32Mevcut:*
Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
RS420 .N665 2001 EB | 1186233-1001 | Elsevier E-Kitap Koleksiyonu | Arıyor... |
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