1. The history and scope of tissue engineering -- 2. The challenge of imitating nature -- 3. Moving into the clinic -- 4. Future perspectives -- 5. Molecular biology of the cell -- 6. Organization of cells into higher-ordered structures -- 7. The dynamics of cell-ECM interactions -- 8. Matrix molecules and their ligands -- 9. Morphogenesis and tissue engineering -- 10. Gene expression, cell determination, and differentiation -- 11. Engineering functional tissues -- 12. Principles of tissue culture and bioreactor design -- 13. Regulation of cell behavior by extracellular proteins -- 14. Growth factors -- 15. Mechanochemical control of cell fate switching -- 16. In vivo synthesis of tissues and organs -- 17. Models as percursors for prosthetic devices -- 18. Quantitative aspects -- 19. Micro-scale patterning of cells and their environment -- 20. Cell interactions wtih polymers -- 21. Matrix effects -- 22. Polymer scaffold fabrication -- 23. Biodegradable polymers -- 24. Micro- and nanofabricated scaffolds -- 25. Three-dimensional scaffolds -- 26. Tissue engineering and transplantation in the fetus -- 27. Immunomodulation -- 28. Immunoisolation -- 29. Engineering challenges in immunobarrier device deveopment -- 30. Embryonic stem cells -- 31. Adult epithelial tissue stem cells -- 32. Embryonic stem cells and a cell source for tissue engineering -- 33. Postnatal stem cells -- 34. Gene therapy -- 35. Gene delivery into cells and tissues -- 36. Breast reconstruction -- 37. Progenitor cells and cardiac homeostasis -- 38. Cardic-tissue engineering -- 39. Blood vessels -- 40. Heart valves -- 41. Generation of islets from stem cells -- 42. Bioartificial pancreas -- 43. Engineering pancreatic beta-cells -- 44. Thymus and parathyroid organogenesis -- 45. Adult stem cells in normal gastrointestinal function and inflammatory disease -- 46. Alimentary tract -- 47. Liver stem cells -- 48. Liver -- 49. Hematopoietic stem cells -- 50. Red blood cells substitutes -- 51. Lymphoid cells -- 52. Stem cells in kindey development and regeneration -- 53. Renal replacement devices -- 54. Genitourinary system -- 55. Mesenchymal stem cells -- 56. Bone regeneration -- 57. Bone and cartilage reconstruction -- 58. Regeneration and replacement of the intervertbral disc -- 59. Articular cartilage injury -- 60. Tendons and ligaments -- 61. Mechanosensory mechanisms in bone -- 62. Skeletal-tissue engineering -- 63. Neural stem cells -- 64. Brain implants -- 65. Spinal cord -- 66. Protection and repair of audition -- 67. Stem cells in the eye -- 68. Corneal-tissue replacement -- 69. Vision enhancement systems -- 70. Biological tooth replacement and repair -- 71. Oral and maxillofacial surgey -- 72. Periodontal-tissue engineering -- 73. Progenitor cells in the respiratory system -- 74. Lungs -- 75. Cutaneous stem cells -- 76. Wound repair -- 77. Bioengineered skin constructs -- 78. Current state of clinical application -- 79. Tissue-engineered skin products -- 80. Tissue-engineered cartilage products -- 81. Tissue-engineered bone products -- 82. Tissue-engineered cardiovascular products -- 83. Tissue-engineered organs -- 84. The tissue-engineering industry -- 85. The regulatory path from concept to market -- 86. Ethical issues.