A critical review of literature revealed a gap in the literature of spiritually based interventions, most notably the subject of a spiritually based intervention for reducing subsyndromal anxiety and increasing coping skills in urban adolescents. The purpose of this study was to investigate the relationship between a spiritually based intervention, a triangulation approach, subsyndromal anxiety, and coping skills in urban adolescents, employing the add-on/integration of a Prayer Wheel intervention. Utilizing a multiple baseline design across subjects to demonstrate the controlling effects of spiritually based intervention/prayer wheel, research revealed a decrease in subsyndromal anxiety levels, and an increase in coping skills in urban adolescent subjects. Although the correlations between a spiritually based intervention, a triangulation approach, subsyndromal anxiety, and coping skills in urban adolescents was not as strong as hypothesized, the current study provides empirical (quantitative and qualitative) evidence that a Prayer Wheel intervention's potential impact has tripartite significance: in research, clinical, and Biblical practice, and suggests that the Prayer Wheel may be an effective tool for the alleviation of symptoms of subsyndromal anxiety among urban adolescents. .