Eylem Seç
Advances in immunology. Volume 59
Başlık:
Advances in immunology. Volume 59
Yazar:
Dixon, Frank J. (Frank James), 1920-2008.
ISBN:
9780080578354
9780120224593
9781281727510
9786611727512
Yayın Bilgileri:
San Diego ; New York ; Boston : Academic Press, ©1995.
Fiziksel Tanımlama:
1 online resource (x, 468 pages) : illustrations.
Seri:
Advances in Immunology ; v.59
Advances in immunology.
İçerik:
Front Cover; Advances in Immunology, Volume 59; Copyright Page; Contents; Contributors; Chapter 1. The CD1 Family: A Third Lineage of Antigen-Presenting Molecules; I. Introduction; II. Genetics and Molecular Biology of the CD1 Family; III. The CDl Proteins: A Family of MHC-Related Molecules; IV. Serologic Definition of CD; V. Biochemical and Immunochemical Studies of CD1 Proteins; VI. Tissue Distribution and Cellular Expression of CD1 Proteins; VII. The Immunological Function of CD1 Proteins; VIII. Concluding Remarks; References; Chapter 2. Positive Selection of Thymocytes; I. Introduction.
II. An Overview of aß TCR+ Thymocyte DevelopmentIII. Experimental Systems for Analyzing Positive Selection; IV. The Discovery of Positive Selection; V. Positive Selection in Genetically Manipulated Animals; VI. Commitment to the CD4+ or CD8+ Lineage: Is It Instructive or Stochastic?; VII. The Cell Type Mediating Positive Selection; VIII. The Ligand for Positive Selection; IX. Concluding Remarks; References; Chapter 3. Molecular and Cellular Aspects of X-Linked Agammaglobulinemia; I. Introduction; II. The Original Report-Bruton (1952)- and Its Implications.
III. Congenital and Acquired Agammaglobulinemia in the Early 1950sIV. Early Studies on the Origin of Agammaglobulinema; V. The Name Issue and the Locus Designation; VI. Incidence and Prognosis; VII. Clinical Manifestations in XLA; VIII. Agammaglobulinemia with Growth Hormone Deficiency; IX. Female XLA; X. Treatment; XI. B Cell Development; XII. B Cell Development in XLA; XIII. The Geneticists' Approach to the XLA Problem; XIV. Cloning of the XLA Gene; XV. PTKs Are Important Regulators of Lymphocyte Functions; XVI. The Btk Family of Cytoplasmic PTKs.
XVII. Mutations Are Found in Different Domains in BtkXVIII. Carrier Detection and Prenatal Diagnosis; XIX. Development of Animal Model Systems for the Analyses of Btk Function; XX. Concluding Remarks; References; Chapter 4. The Common?-Chain for Multiple Cytokine Receptors; I. Introduction; II. Structure and Function of IL-2 Receptor Subunits; III. Sharing of IL-2Ry among Multiple Cytokine Receptors; IV. Causative Relationship between IL-2R? Mutations and Human XSCID; V. Signal Transduction Initiated by the Receptors Sharing the yc-Chain; VI. Concluding Remarks; References.
Chapter 5. Self-Tolerance Checkpoints in B Lymphocyte DevelopmentI. Introduction; II. Checkpoints during Formation of the Preimmune Repertoire; III. Checkpoints during Formation of the Immune Repertoire; IV. Relevance of B Cell Tolerance Checkpoints for Autoimmune Disease; References; Chapter 6. The Regulation of Pulmonary Immunity; I. Introduction; II. Immune Cells and Structures of the Lung; III. Lung Immunity to Noninfectious Particulate and Soluble Antigens; IV. Models for Immunity in Lung Infections; V. Models for Hypersensitivity Lung Diseases.
Özet:
With contributions from Steven A. Porcelli and other internationally recognized leaders in the field, this volume continues the tradition of indispensable reviews. Papers on the CD1 family, positive selection of thymocytes, and molecular and cellular aspects of XLA highlight the latest volume.
Tür:
Added Author:
Elektronik Erişim:
to access electronic resource MacEwan University Access (Unlimited Concurrent Users) from ScienceDirect ScienceDirect http://www.sciencedirect.com/science/book/9780120224593Mevcut:*
Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
QR181 .A38 EB VOL. 59 | 1190460-1001 | Elsevier E-Kitap Koleksiyonu | Arıyor... |
On Order
Liste seç
Bunu varsayılan liste yap.
Öğeler başarıyla eklendi
Öğeler eklenirken hata oldu. Lütfen tekrar deneyiniz.
:
Select An Item
Data usage warning: You will receive one text message for each title you selected.
Standard text messaging rates apply.