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Near-Infrared Spectroscopy and Mathematical Modeling for the Characterization of Human Cerebral Hemodynamics in the Microvasculature
Başlık:
Near-Infrared Spectroscopy and Mathematical Modeling for the Characterization of Human Cerebral Hemodynamics in the Microvasculature
Yazar:
Tgavalekos, Kristen T., author.
ISBN:
9780438020184
Yazar Ek Girişi:
Fiziksel Tanımlama:
1 electronic resource (132 pages)
Genel Not:
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisors: Sergio Fantini Committee members: Irene Georgakoudi; Joshua Kornbluth; Brian Tracey.
Özet:
Near-infrared spectroscopy (NIRS), in combination with coherent hemodynamics spectroscopy (CHS), provides information about the cerebral microvasculature in terms of cerebral blood flow, cerebral blood volume, and the cerebral metabolic rate of oxygen. We characterize the frequency-dependent relationship between tissue concentrations of oxyhemoglobin and deoxyhemoglobin, measured with NIRS, as well as the relationship between total hemoglobin concentration and arterial blood pressure in healthy subjects. We use the hemodynamic model of CHS for the analysis of the results to yield physiologic parameters such as absolute cerebral blood flow and cerebral autoregulation. Further, we demonstrate the application of NIRS-CHS in the clinical setting of the neurocritical care unit.
Notlar:
School code: 0234
Konu Başlığı:
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Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
XX(680278.1) | 680278-1001 | Proquest E-Tez Koleksiyonu | Arıyor... |
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