Front Cover; Advances in Immunology, Volume 10; Copyright Page; Contents; List of Cotributors; Preface; Contents of Previous Volumes; Chapter 1. Cell Selection by Antigen in the Immune Response; I. Introduction; II. Antibody-Binding Affinity; III. Maturation of the Immune Response; IV. Commibnent of Individual Plasma Cells and Sensitized Lymphocytes to the Synthesis of Immunoglobulins of a Single Class and Individual Specificity; V. Effect of Antigen Dose upon the Amount and Affinity of Serum Antibody.

VI. Maturation of the Immune Response: The Selective Stimulation of the Proliferation of Those Cells That Produce Highest-Affinity AntibodyVII. Effect of Humoral Antibody on the Control of Antibody Synthesis; VIII. "Original Antigenic Sin"; IX. Immunological Tolerance (Unresponsiveness); X. Summary of Antigen Selection Hypothesis; XI. Practical Conclusions and Further Problems to Investigate; References; Chapter 2. Phylogeny of Immunoglobulins; I. Introduction; II. The Question of Invertebrate Antibodies; III. Vertebrate Immunoglobulins; IV. Concluding Remarks; References.

Chapter 3. Slow Reacting Substance of AnaphylaxisI. Introduction; II. Physical and Chemical Properties; III. Pharmacology; IV. Immunological Release of Slow Reacting Substance of Anaphylaxis in the Rat; V. Immunological Release of Slow Reacting Substance of Anaphylaxis in Other Species Including Man; VI. Concluding Comments; References; Chapter 4. Some Relationships among Hemostasis. Fibrinolytic Phenomena, Immunity, and the Inflammatory Response; I. Introduction; II. Hemostatic Mechanisms; III. Fibrinolytic Phenomena; IV. The Inflammatory Process; V. Complement.

VI. Blood Clotting and Antigen-Antibody ReactionsVII. Anaphylatoxins and Related Mediators of Inflammation; VIII. Anaphylaxis; IX. Endotoxins and the Shwartzman Phenomenon; X. Allograft Rejection; XI. Clinical and Experimental Nephritis; XII. The Arthus Phenomenon; XIII. Delayed Hypersensitivity; XIV. Concluding Remark; References; Chapter 5. Antigens of Virus-Induced Tumors; I. Introduction; II. Transplantation Type or Surface Antigen; III. T Antigens; IV. Structural Virus Antigens; V. Immunological Phenomena in Viral Oncogenesis; VI. Significance of Virus-Coded Antigens in Oncogenesis.

VII. Human TumorsReferences; Chapter 6. Genetic and Antigenetic Aspects of Human Histocompatibility Systems; I. Introduction; II. Major Histocompatibility Systems; III. The HL-A System of Man; IV. The Use of Typing for HL-A Factors in Donor Selection; V. Other Human Histocompatibility Antigens; VI. Properties and Genetic Control of Histocompatibility Antigens; VII. Possible Future Developments; VIII. Appendix: Techniques for the Detection of HL-A Specificities; References; Author Index; Subject Index; Cumulative Index-Volumes 1-10.