![](/client/images/blank.gif)
Eylem Seç
![Inexact Methods for the Chemical Master Equation with Constant or Time-Varying Propensities, and Application to Parameter Inference için kapak resmi Inexact Methods for the Chemical Master Equation with Constant or Time-Varying Propensities, and Application to Parameter Inference için kapak resmi](/client/assets/d79c3e4af2b6d196/ctx/images/no_image.png)
Inexact Methods for the Chemical Master Equation with Constant or Time-Varying Propensities, and Application to Parameter Inference
Başlık:
Inexact Methods for the Chemical Master Equation with Constant or Time-Varying Propensities, and Application to Parameter Inference
Yazar:
Dinh, Khanh N., author.
ISBN:
9780438040908
Yazar Ek Girişi:
Fiziksel Tanımlama:
1 electronic resource (160 pages)
Genel Not:
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisors: Roger B. Sidje Committee members: Layachi Hadji; David Halpern; Tatiana Marquez-Lago; Min Sun.
Özet:
Complex reaction networks arise in molecular biology and many other different ?elds of science such as ecology and social study. A familiar approach to modeling such problems is to ?nd their master equation. In systems biology, the equation is called the chemical master equation (CME), and solving the CME is a difficult task, because of the curse of dimensionality. The goal of this dissertation is to alleviate this curse via the use of the ?nite state projection (FSP), in both cases where the CME matrix is constant (if the reaction rates are time-independent) or time-varying (if the reaction rates change over time). The work includes a theoretical characterization of the FSP truncation technique by showing that it can be put in the framework of inexact Krylov methods that relax matrix-vector products and compute them expediently by trading accuracy for speed. We also examine practical applications of our work in delay CME and parameter inference through local and global optimization schemes.
Notlar:
School code: 0004
Tüzel Kişi Ek Girişi:
Mevcut:*
Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
XX(678814.1) | 678814-1001 | Proquest E-Tez Koleksiyonu | Arıyor... |
On Order
Liste seç
Bunu varsayılan liste yap.
Öğeler başarıyla eklendi
Öğeler eklenirken hata oldu. Lütfen tekrar deneyiniz.
:
Select An Item
Data usage warning: You will receive one text message for each title you selected.
Standard text messaging rates apply.