Front Cover; The Biochemistry and Physiology of Bone; Copyright Page; PREFACE; LIST OF CONTRIBUTORS; Table of Contents; CHAPTER I. GENERAL ANATOMY AND HISTOLOGY OF BONE; 1. General Introduction; II. The Primary Constituents of Bony Tissue; III. Types of Bony Tissue; IV. Organization of Bony Tissue; V. ""Membrane"" and ""Cartilage"" Bone; REFERENCES; PLATE I; CHAPTER II. BONE AS A MECHANICAL ENGINEERING PROBLEM; I. Introduction; II. Shape and Size; III. Growth of the Skull; IV. Cancellous Bone; V. Bone Strength; VI. Hormonal Effects; VII. Nervous Influences on Bone.

VIII. Strength of Healing FracturesREFERENCES; CHAPTER III. THE GROUND SUBSTANCE OF CONNECTIVE TISSUE AND CARTILAGE; I. Introduction; II. Historic Survey; III. The Term Ground Substance -- IV. Distribution and Physical Characteristics; V. Microscopy of Ground Substances; VI. Chemistry of Ground Substances; VII. Genesis of Ground Substance Materials; VIII. Some Physiological Aspects; IX. Possible Organization of Ground Substance; X. Concluding Remarks; REFERENCES; CHAPTER IV. THE ORGANIC MATRIX OF BONE; I. Introduction; II. The Chemistry of Bone Collagen.

III. Chemical Nature of the Other Constituents of the MatrixIV. The Place of the ""Organic Matrix"" in Bone Structure; REFERENCES; CHAPTER V. COLLAGEN FIBERS OF CONNECTIVE TISSUE; I. Introduction; II. Methods of Investigation; III. Structure of Collagen Fibers; IV. The Formation of Collagen Fibers; V. Relation of Collagen to its Environment; VI. Alterations of Collagen Fibers Observed by X-ray Diffraction and Electron Microscopy; VII. Destruction of Collagen Fibers; PLATE I; PLATE II; REFERENCES; CHAPTER VI. ULTRASTRUCTURE AND DISTRIBUTION OF MINERAL SALTS IN BONE TISSUE; I. Introduction.

II. Distribution of the Inorganic Salts in Bone TissueIII. Survey of the Methods for the Study of the Ultrastructure of Bone; IV. Structure of the Inorganic Constituent of Bone; V. Relation between Mineral Salts and Collagen in Bone Tissue; PLATE I; REFERENCES; CHAPER VII. THE OSTEOBLAST; I. Introduction; II. General Cytology; III. Cytochemistry; IV. Integration of Morphological and Histochemical Studies; V. Functional Significance; VI. Morphological Status and Transformations; VII. Conclusion; PLATE I; PLATE II; PLATE III; REFERENCES; CHAPTER VIII. THE OSTEOCLAST; I. Introduction.

II. Microscopical AppearancesIII. Origin and Fate; IV. Function; ADDENDUM; PLATE I; REFERENCES; CHAPTER IX. PHOSPHATASE AND BONE; I. Historical; II. Identity of Bone Phosphatase and Comparison with Soft Tissue Phosphatase; III. Histological Distribution of Phosphatase in Mature and Developing Bone; IV. Phosphatase and Bone Repair; V. Significance of Phosphatase in Bone Formation; VI. Summary; ADDENDUM; PLATE I; REFERENCES; CHAPTER X. THE CHEMISTRY OF CALCIFICATION; I. Nature of Bone Salt; II. Relation of Bone Composition to Diet; III. Cartilage and Bone Matrix.