Front Cover; Biochemistry of Characterised Neurons; Copyright Page; Dedication; Table of Contents; Abbreviations; Preface; Foreword; CHAPTER 1. VALIDITY OF SINGLE NEURON CHEMICAL ANALYSIS; 1. AN OLD QUESTION: WHY SINGLE CELLS?; 2. THE NEW MICROTOOLS; 3. NEW APPLICATIONS AND TRENDS OF MICROCHEMISTRY IN NEUROBIOLOGY; 4. PRESENCE OF SEVERAL NEUROTRANSMITTERS IN THE SAME NEURON; 5. THE FUTURE: NEW APPLICATIONS OF MICROCHEMISTRY IN NEUROBIOLOGY; References; CHAPTER 2. THE RETZIUS CELL OF THE LEECH HIRUDO MEDICINALIS; 1. INTRODUCTION; 2. HISTOCHEMICAL STUDIES OF THE RETZIUS CELLS.

3. SUBCELLULAR LOCATION OF 5-HT IN THE RETZIUS CELLS4. ANALYSES OF 5-HT IN ISOLATED RETZIUS CELL BODIES; 5. ORIGIN OF 5-HT IN THE RETZIUS CELLS; 6. THE ROLE OF 5-HT IN THE LEECH NERVOUS SYSTEM; 7. THE DETERMINATION OF 5-HT IN THE RETZIUS CELLS BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY; 8. SUMMARY; Acknowledgements; References; CHAPTER 3. THE NEUROBIOLOGY OF A SEROTONERGIC NEURON; 1. INTRODUCTION; 2. MORPHOLOGY AND HISTOLOGY OF THE GSC IN HELIX POMATIA; 3. SEROTONIN AND OTHER TRANSMITTER CANDIDATES IN THE GSC; 4. FACTORS AFFECTING THE SEROTONIN LEVEL OF GSCs.

5. METABOLISM OF SEROTONIN BY THE GSC6. AXONAL TRANSPORT AND COMPARTMENTATION OF SEROTONIN IN THE GSCs: INJECTION OF 3H-SEROTONIN; 7. UPTAKE OF SEROTONIN BY THE GSCs; 8. SYNAPTIC RELEASE OF SEROTONIN FROM THE GSCs; 9. GLUCOSE METABOLISM IN THE GSCs: EFFECT OF STIMULATION; 10. A FUNCTIONAL ROLE FOR THE GSC; 11. SUMMARY; References; CHAPTER 4. THE CHARACTERISED DOPAMINE NEURON IN PLANORBIS CORNEUS; 1. INTRODUCTION; 2. ANATOMY OF THE DOPAMINE NEURON; 3. DOPAMINE CONTENT AND METABOLISM; 4. SYNAPTIC CONNEXIONS MADE BY THE DOPAMINE NEURON; 5. PHARMACOLOGY OF TRANSMISSION; 6. CONCLUSIONS; 7. SUMMARY.

AcknowledgementsReferences; CHAPTER 5. OCTOPAMINE NEURONS IN THE LOBSTER; 1. INTRODUCTION; 2. LOCALISATION OF OCTOPAMINE CELLS; 3. DESCRIPTION OF PREPARATION; 4. ANALYSIS OF NEURONAL PROPERTIES; 5. OCTOPAMINE STUDIES IN OTHER INVERTEBRATES; 6. CONCLUSION; 7. SUMMARY; Acknowledgements; References; CHAPTER 6. HISTAMINE-CONTAINING NEURONS IN APLYSIA; 1. INTRODUCTION; 2. ORGANIZATION AND IDENTIFICATION OF NEURONS IN THE CEREBRAL GANGLIA; 3. ISOLATION OF NERVE CELL BODIES; 4. CHEMICAL TECHNIQUES; 5. DISTRIBUTION OF HISTAMINE IN THE NERVOUS SYSTEM OF APLYSIA; 6. LOCATION OF HISTAMINE CELLS.

7. ENDOGENOUS LEVELS OF HISTAMINE IN SINGLE NERVE CELL BODIES8. SYNTHESIS OF RADIOLABELLED HISTAMINE IN INDIVIDUAL NEURONS; 9. HISTIDINE DECARBOXYLASE ACTIVITY IN SINGLE NERVE CELL BODIES; 10. CELLULAR HISTIDINE CONCENTRATION IN APLYSIA NEURONS; 11. DISCUSSION; 12. SUMMARY; Acknowledgements; References; CHAPTER 7. THE BIOCHEMISTRY OF TORPEDO CHOLINERGIC NEURONS; 1. INTRODUCTION; 2. THE ELECTROMOTOR SYSTEM OF TORPEDO; 3. CYTOBIOCHEMISTRY OF THE TORPEDO ELECTROMOTOR SYSTEM AS REVEALED BY SUBCELLULAR FRACTIONATION STUDIES; 4. CONCLUDING REMARKS; 5. SUMMARY; Acknowledgements; References.