Front Cover; Progress in Medicinal Chemistry, Volume 40; Copyright Page; Contents; Preface; List of Contributors; Chapter 1. The Discovery and Development of Atorvastatin, a Potent Novel Hypolipidemic Agent; Chapter 2. Discovery of CEP-1347/KT-7515, an Inhibitor of the JNK/SAPK Pathway for the Treatment; Chapter 3. Discovery of Second Generation Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors of HIV-1; Chapter 4. Molecular Modeling of Opioid Receptor-Ligand Complexes; Subject Index; Author Index (Vols. 1-40); Subject Index (Vols. 1-40)