Front Cover; Advances in Immunology, Volume 32; Copyright Page; Contents; List of Contributors; Preface; Chapter 1. Polyclonal B-Cell Activators in the Study of the Regulation of Immunoglobulin Synthesis in the Human System; I. Introduction; II. Techniques Used to Assess the Polyclonal Activation of B Cells into Immunoglobulin- and Antibody-Producing Cells; III. Ability of Different Agents to Stimulate Human Peripheral Blood B Cells to Develop into Immunoglobulin-Producing and -Secreting Cells; IV. T-cell Requirement for Immunoglobulin Synthesis by B Cells.

V. Differences in Polyclonal B-Cell Activators in Terms of Their Capacity to Activate Prosuppressor T Cells into Suppressor Effector CellsVI. Regulatory Role of Circulating Monocytes in B-Cell Activation by Polyclonal Stimulators; VII. Application of Polyclonal Activators of B Cells to the Analysis of the Pathogenic Defects That Lead to Disordered Immunoglobulin Synthesis; VIII. Summary; References; Chapter 2. Typing for Human Alloantigens with the Primed Lymphocyte Typing Technique; I. The Major Histocompatibility Complex in Man: HLA; II. HLA-A, B, C, and DR Serology.

III. Mixed Lymphocyte Culture Reaction (MLR)IV. Cell-Mediated Cytotoxicity (CMC); V. Proliferative Response of Primed Lymphocytes (Secondary MLR); VI. Genetics of Secondary MLR; VII. Primed Lymphocyte Typing (PLT); VIII. Technical Aspects of PLT; IX. Data Reduction in PLT; X. Generation and Selection of PLT Cells; XI. Antigen Assignment in PLT; XII. Typing with the PLT Test; XIII. Histocompatibility Testing with the Secondary MLR; XIV. Associations between PLT-Defined Determinants and Disease; XV. Conclusion; References.

Chapter 3. Protein A of Staphylococcus aureus and Related Immunoglobulin Receptors Produced by Streptococci and PneumonococciI. Introduction; II. Occurrence of Protein A; III. Production of Protein A; IV. Isolation and Properties of Protein A; V. Reactivity with Immunoglobulins; VI. Biological Activity of Protein A and Protein A-IgG Complexes; VII. Analytical Applications of Protein A; VIII. Immunoglobulin Receptors Produced by Streptococci; IX. Results with Pneumonococci; X. Concluding Remarks; References; Chapter 4. Regulation of Immunity to the Azobenzenearsonate Hapten; I. Introduction.

II. Strain Distribution of the CRIIII. Heterogeneity of A/J Anti-ABA Antibodies; IV. Heterogeneity of Molecules Expressing the CRI; V. Serological Studies of Monoclonal CRI+ Antibodies; VI. Private Idiotypic Determinants on CRI+ MA; VII. Conserved Determinants in the CRI+ Family; VIII. Amino Acid Sequences of CRI+ MA; IX. Linkage of Expression of CRI to Loci Controlling H and Kappa chains; X. Regulation of the Humoral Anti-ABA Antibody Response to Idiotypic Determinants; XI. Suppression of the CRI-Bearing Ab Mediated by B Cells.