![](/client/images/blank.gif)
Eylem Seç
![Interleukin-1 in the brain için kapak resmi Interleukin-1 in the brain için kapak resmi](/client/assets/d79c3e4af2b6d196/ctx/images/no_image.png)
Interleukin-1 in the brain
Başlık:
Interleukin-1 in the brain
Yazar:
Rothwell, Nancy.
Basım Bilgisi:
1st ed.
Yayın Bilgileri:
Oxford ; New York : Pergamon Press, 1992.
Fiziksel Tanımlama:
1 online resource (viii, 207 pages) : illustrations.
Seri:
Pergamon studies in neuroscience ; no. 5
Pergamon studies in neuroscience ; no. 5.
İçerik:
Location of interleukin-1 in the nervous system / M. Schultzberg -- Brain interleukin-1 receptors: mapping, characterization and modulation / F. Haour [and others] -- Interleukin-1[beta] activation of the central nervous system / P.E. Gottschall, G. Komaki and A. Arimura -- Electrophysiological studies of the effects of interleukin-1 and [alpha]-interferon on the EEG and pituitary-adrenocortical activity / D. Saphier -- Immune-hypothalomo-pituitary adrenal axis: its role in immunoregulation and tolerance to self-antigens / F. Berkenbosch [and others] -- Pyrogenic action of cytokines / C.M. Blatteis -- Metabolic responses to interleukin-1 / N.J. Rothwell -- Behavioural effects of cytokines / R. Dantzer [and others] -- Interleukin-1 involvement in the regulation of sleep / M.R. Opp and J.M. Krueger -- Regulation of the synthesis of nerve growth factor (NGF) by interleukin-1 (IL-1): facts and questions / M. Meyer [and others] -- Cytokines and neuronal degeneration / E.E. Wollman [and others].
Özet:
Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the data available on the neural localisation of IL-1 and the nature of its central receptors. The main part of the book examines the different neural effects of IL-1 and the mechanisms which are involved in these actions, comparing IL-1 where possible to other inflammatory cytokines which also have neurotrophic effects. The final section evaluates the possible role of IL-1 in neural plasticity and neuronal degeneration.
Konu Başlığı:
Tür:
Elektronik Erişim:
ScienceDirect http://www.sciencedirect.com/science/book/9780080419961Mevcut:*
Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
QP356.3 .I494 1992 | 1182845-1001 | Elsevier E-Kitap Koleksiyonu | Arıyor... |
On Order
Liste seç
Bunu varsayılan liste yap.
Öğeler başarıyla eklendi
Öğeler eklenirken hata oldu. Lütfen tekrar deneyiniz.
:
Select An Item
Data usage warning: You will receive one text message for each title you selected.
Standard text messaging rates apply.