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![A quantitative study of acetyl cholinesterase in muscle endplates için kapak resmi A quantitative study of acetyl cholinesterase in muscle endplates için kapak resmi](/client/assets/d79c3e4af2b6d196/ctx/images/no_image.png)
A quantitative study of acetyl cholinesterase in muscle endplates
Başlık:
A quantitative study of acetyl cholinesterase in muscle endplates
Yazar:
Kerr, Audrey E., author.
ISBN:
9780438054158
Yazar Ek Girişi:
Fiziksel Tanımlama:
1 electronic resource (61 pages)
Genel Not:
Source: Dissertation Abstracts International, Volume: 76-08C.
Advisors: Gordon Murray.
Özet:
The data to be analysed were provided by a quantitative study of acetyl cholinesterase (AChE) in the endplates of two different muscles (Soleus, Tibialis anterior) under three different treatments (Unfixed, Immersion fixed and Perfusion fixed). The experiment was later repeated giving a total of twelve data sets to be analysed, each set consisting of a number of density readings taken at each of several different incubation times. The principle aim of the study was to compare treatments within each muscle, and it was also of interest to look for differences between the muscles, although there was no reason to think that the muscles should be the same. In Chapter 1 the experiment is described in general terms and the form of the data is given. Chapter 2 discusses the linear regression model and its underlying assumptions, and assesses, both formally and informally, to what extent the data meet these assumptions. The main conclusion from Chapter 2 is that some transformation of the data is required and Chapter 3 assesses the suitability of different transformations of the response variable and considers weighted least squares. The "best" transformation is found to be the square root transformation. In Chapter 4 the data from Experiment 1 is shown to be more variable than that of Experiment 2 and is discarded on the grounds of experimental inaccuracy. Weighted comparisons are then made of the transformed data of Experiment 2 and the conclusion is that a clear difference exists between the Unfixed and the two fixed treatments of both muscles and that there is no important difference between the two fixed treatments. In addition, the two muscles give obviously different readings.
Notlar:
School code: 0547
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Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
XX(684487.1) | 684487-1001 | Proquest E-Tez Koleksiyonu | Arıyor... |
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