Eylem Seç
An epidemiological study of symptoms, dust exposure and variations in lung physiology across the week amongst textile spinners in Lancashire
Başlık:
An epidemiological study of symptoms, dust exposure and variations in lung physiology across the week amongst textile spinners in Lancashire
Yazar:
Warburton, Christopher James, author.
ISBN:
9780438082748
Yazar Ek Girişi:
Fiziksel Tanımlama:
1 electronic resource (542 pages)
Genel Not:
Source: Dissertation Abstracts International, Volume: 76-08C.
Özet:
Operatives from mills in and around the Oldham area have been studied using a modified Medical Research council Respiratory Symptoms Questionnaire for the identification of symptoms. All willing operatives also performed simple spirometry. A group of operatives with work-related respiratory symptoms (including byssinosis)(WRRS) and a group of asymptomatic matched controls have performed spirometry and bronchial challenge testing with histamine, before and after a shift on the first and fourth shifts of their working week. The cross-sectional symptom and lung function results showed that the current prevalence of byssinosis in the cotton exposed population was only 2.3%, however nearly 12% of all operatives seen were experiencing one or more WRRSs. All except one of the WRRS was more prevalent in the cotton exposed workers as opposed to those exposed to manmade fibre, and all were more prevalent in current cigarette smokers. The lung function analysis revealed poor prediction equation performance for asian operatives therefore regression equations were derived from and for this population of asians. Cigarette smoking and the presence of WRRS was found to be associated with reduced lung function. The across shift and across week variations were also studied in detail. The development of bronchial obstruction over time (assessed using the beginning of week levels) was shown to be related to cumulative cigarette exposure, the time spent in the cotton industry and the presence of WRRS. Baseline bronchial reactivity was related to both the presence of WRRS and the cumulative cigarette exposure. Cumulative cigarette exposure was the only demographic factor demonstrated to have effects upon across shift falls in FEV1, FVC, FMEF and FEF on Day 1 of the working week, and also across week falls in these parameters. The presence of WRRS was associated with changes in FEV1 and FVC across shift on Day 1 and across the week. Significant tachyphylaxis to the effects of cotton dust was demonstrated and this effect was more marked in the operatives with WRRS. The size of across shift and across week changes in lung function were smaller than those demonstrated in previous studies possibly as a result of the ongoing reduction in the level of cotton dust exposure in Lancashire mills. The pattern of physiology demonstrated by the operatives with WRRS suggests that these symptoms may represent occupational asthma. Across week changes in lung function may better identify those operatives who have or may develop accelerated longitudinal lung function loss than across shift measurements.
Notlar:
School code: 1543
Tüzel Kişi Ek Girişi:
Mevcut:*
Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
XX(686838.1) | 686838-1001 | Proquest E-Tez Koleksiyonu | Arıyor... |
On Order
Liste seç
Bunu varsayılan liste yap.
Öğeler başarıyla eklendi
Öğeler eklenirken hata oldu. Lütfen tekrar deneyiniz.
:
Select An Item
Data usage warning: You will receive one text message for each title you selected.
Standard text messaging rates apply.