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Dental Resin Inspired Hydrogel Adhesive for Wet Mucosal Environments
Başlık:
Dental Resin Inspired Hydrogel Adhesive for Wet Mucosal Environments
Yazar:
Marth, Alexis Lynn, author.
ISBN:
9780438050105
Yazar Ek Girişi:
Fiziksel Tanımlama:
1 electronic resource (122 pages)
Genel Not:
Source: Masters Abstracts International, Volume: 57-06M(E).
Advisors: Anne E. Meyer Committee members: Robert E. Baier; Laura E. Edsberg; Mukund Seshadri.
Özet:
Challenges remain in theoretical and practical concepts regarding the adhesion strengths and performances of materials for "semi-permanent" use in a wet environment. One example is the clinical need for intra-oral bandages that will stay in place for more than 1 or 2 days. The investigation reported here focused on a proposed novel approach to sustained tissue-surface adhesion in a model dental resin hydrogel-based dressing by examining the processes and mechanisms for adhesion. A secondary aim of this study was the protection of the adhesive through the use of a biodegradable material applied as a cap over the dressing on preserved, moist pericardial tissue.
Preparations of polyethylene oxide, acacia, gelatin, and bioactive Bioglass were mixed with bisphenol glycol dimethacrylate, triethlyene glycol dimethacrylate, and the photo-initiator camphorquinone to form a gelled paste covered by an initially rigid cap of dehydrated hyaluronic acid. The model dressing was compared with marketed liquid or hydrogel bandage products as well as marketed dental adhesives. Material analyses included surface energy and infrared methods. Material modification included Radio-frequency Glow Discharge treatment of the rigid material and light curing of the adhesive pastes, as monitored by mechanical testing. The cured adhesive exhibited the strongest adhesive strength in tension at 1 hour after storage in moist 37 °C incubator conditions. The strength and time of rupture was approximately between 0.73 N at 58 seconds to 1.4 N at 30 seconds. After 5 days in the incubator, the test material had strength of approximately 0.5 N for 10--30 seconds. This study demonstrated progress toward a new approach for an intra-oral bandage, which may have the potential for a faster and cleaner healing process.
Notlar:
School code: 0656
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Yer Numarası | Demirbaş Numarası | Shelf Location | Lokasyon / Statüsü / İade Tarihi |
---|---|---|---|
XX(694183.1) | 694183-1001 | Proquest E-Tez Koleksiyonu | Arıyor... |
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