explanatory model of MDD. In a review of relevant literature examining biologic alterations produced by

responsible for its potent impact on human memory. Chapter 4 extends the work in Chapter 3 by evaluating

responses such as axonal injury, but is largely ignored in TBI literature. In Chapter 1, an outline of

, methodological considerations, and current gaps in the literature. This review also incorporates key findings

different tissue types. Furthermore, there are no reports in the literature of increased risk of stroke in